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    abhd10a abhydrolase domain containing 10, depalmitoylase a [ Danio rerio (zebrafish) ]

    Gene ID: 568517, updated on 4-Jan-2025

    Summary

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    Official Symbol
    abhd10aprovided by ZNC
    Official Full Name
    abhydrolase domain containing 10, depalmitoylase aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060526-144
    See related
    Ensembl:ENSDARG00000076435 AllianceGenome:ZFIN:ZDB-GENE-060526-144
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    abhd10; fb10b08; wu:fb10b08; si:ch211-271b14.3
    Summary
    Predicted to enable mycophenolic acid acyl-glucuronide esterase activity and palmitoyl-(protein) hydrolase activity. Predicted to be located in membrane and mitochondrion. Orthologous to human ABHD10 (abhydrolase domain containing 10, depalmitoylase). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See abhd10a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (67884083..67895834, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (67209046..67218142, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene zgc:152816 Neighboring gene transgelin 3a Neighboring gene GS homeobox 1 Neighboring gene mitochondrial translational initiation factor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mycophenolic acid acyl-glucuronide esterase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables palmitoyl-(protein) hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    abhydrolase domain containing 10, depalmitoylase a
    Names
    abhydrolase domain containing 10a
    NP_001313452.1
    NP_001313453.1
    XP_005165696.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001326523.1 → NP_001313452.1  abhydrolase domain containing 10, depalmitoylase a isoform 1

      Status: VALIDATED

      Source sequence(s)
      CU861887
      UniProtKB/TrEMBL
      A0A0R4ILM1, A0A8M1P930
      Related
      ENSDARP00000136531.1, ENSDART00000158917.3
      Conserved Domains (2) summary
      COG0596
      Location:44 → 256
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:56 → 258
      Abhydrolase_5; Alpha/beta hydrolase family

    2. NM_001326524.1 → NP_001313453.1  abhydrolase domain containing 10, depalmitoylase a isoform 2

      Status: VALIDATED

      Source sequence(s)
      CU861887
      UniProtKB/TrEMBL
      A0A8M1P818
      Related
      ENSDART00000169254.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      67884083..67895834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165639.5 → XP_005165696.1  abhydrolase domain containing 10, depalmitoylase a isoform X1

      UniProtKB/TrEMBL
      A0A8M2BCX5
      Conserved Domains (2) summary
      COG0596
      Location:46 → 258
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:58 → 260
      Abhydrolase_5; Alpha/beta hydrolase family
    Nucleotide Protein
    Heading Accession and Version

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