cdk5rap3 CDK5 regulatory subunit associated protein 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cdk5rap3provided by ZNC
Official Full Name: CDK5 regulatory subunit associated protein 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040625-90
See related: Ensembl:ENSDARG00000045092 AllianceGenome:ZFIN:ZDB-GENE-040625-90
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cdkrap3; fb33h04; fc09c05; zgc:86863; id:ibd2920; wu:fb33h04; wu:fc09c05
Summary: Acts upstream of or within gastrulation; negative regulation of Wnt signaling pathway; and regulation of mitotic cell cycle. Predicted to be active in endomembrane system. Is expressed in several structures, including digestive system; hatching gland; mesoderm; nervous system; and pharyngeal arch. Orthologous to human CDK5RAP3 (CDK5 regulatory subunit associated protein 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (28825829..28835143)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (28710927..28720241)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb33h04 (e-PCR)
- UniSTS:189030

fb33h04.x1 (e-PCR)
- UniSTS:203126

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell-cell adhesion involved in gastrulation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of dorsal/ventral axis specification	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of dorsal/ventral axis specification	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within epiboly involved in gastrulation with mouth forming second	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within negative regulation of Wnt signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within negative regulation of Wnt signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: CDK5 regulatory subunit-associated protein 3

Names: lzap

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.