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    dynll1 dynein, light chain, LC8-type 1 [ Danio rerio (zebrafish) ]

    Gene ID: 406297, updated on 4-Jan-2025

    Summary

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    Official Symbol
    dynll1provided by ZNC
    Official Full Name
    dynein, light chain, LC8-type 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1961
    See related
    Ensembl:ENSDARG00000058454 AllianceGenome:ZFIN:ZDB-GENE-040426-1961
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dynll2; zgc:73406; wu:fd56c09
    Summary
    Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoplasm and microtubule. Predicted to be part of dynein complex. Orthologous to human DYNLL1 (dynein light chain LC8-type 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See dynll1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (2487276..2491471)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (2428748..2432928)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882034 Neighboring gene si:dkeyp-51b9.3 Neighboring gene ribosomal protein L6 Neighboring gene acetyl-CoA acyltransferase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model. Li Y, et al. Dis Model Mech, 2019 Oct 17. PMID 31515263, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of dynein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of microtubule associated complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dynein light chain 1, cytoplasmic
    Names
    dynein light chain 2
    dynein, light chain, LC8-type 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213024.2 → NP_998189.1  dynein light chain 1, cytoplasmic

      See identical proteins and their annotated locations for NP_998189.1

      Status: VALIDATED

      Source sequence(s)
      CT573399
      UniProtKB/TrEMBL
      A0A8M1PEG1, Q6PBH4
      Related
      ENSDARP00000075768.4, ENSDART00000081325.5
      Conserved Domains (1) summary
      cd21452
      Location:5 → 88
      DLC-like_DYNLL1_DYNLL2; dynein light chain (DLC)-like domain found in the cytoplasmic dynein light chain 1 (DYNLL1) family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      2487276..2491471
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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