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    Zfp97 zinc finger protein 97 [ Mus musculus (house mouse) ]

    Gene ID: 22759, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp97provided by MGI
    Official Full Name
    zinc finger protein 97provided by MGI
    Primary source
    MGI:MGI:105921
    See related
    Ensembl:ENSMUSG00000095990 AllianceGenome:MGI:105921
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NGD16-4
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in central nervous system and genitourinary system. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in bladder adult (RPKM 3.3), placenta adult (RPKM 2.2) and 22 other tissues See more
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    Genomic context

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    See Zfp97 in Genome Data Viewer
    Location:
    17 A3.1; 17 9.77 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (17341372..17367400)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (17121108..17147138)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4193 Neighboring gene predicted gene, 51425 Neighboring gene STARR-seq mESC enhancer starr_41945 Neighboring gene zinc finger protein 960 Neighboring gene STARR-seq mESC enhancer starr_41946 Neighboring gene STARR-positive B cell enhancer mm9_chr17:17316083-17316384 Neighboring gene STARR-seq mESC enhancer starr_41947 Neighboring gene predicted gene, 38396 Neighboring gene STARR-positive B cell enhancer ABC_E954 Neighboring gene predicted gene 5165

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Isolation of a cDNA encoding a novel zinc-finger protein from neuroblastoma x glioma NG108-15 cells. Wick MJ, et al. Gene, 1995 Jan 23. PMID 7835705
    2. Expression of zfh-4, a new member of the zinc finger-homeodomain family, in developing brain and muscle. Kostich WA, et al. Dev Dyn, 1995 Feb. PMID 7537552
    3. Large-scale identification of mammalian proteins localized to nuclear sub-compartments. Sutherland HG, et al. Hum Mol Genet, 2001 Sep 1. PMID 11555636
    4. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Neidhardt L, et al. Mech Dev, 2000 Nov. PMID 11044609
    5. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger protein 97

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011765.5 → NP_035895.3  zinc finger protein 97

      Status: VALIDATED

      Source sequence(s)
      AC117220, CF165138, DV660800
      Consensus CDS
      CCDS49965.1
      UniProtKB/TrEMBL
      E9PVC4, E9PZP6
      Related
      ENSMUSP00000114301.2, ENSMUST00000147630.2
      Conserved Domains (5) summary
      smart00349
      Location:13 → 54
      KRAB; krueppel associated box
      COG5048
      Location:156 → 541
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:464 → 484
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 501
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      17341372..17367400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249764.2 → XP_030105624.1  zinc finger protein 97 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:156 → 541
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:464 → 484
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 53
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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