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    Drc12 dynein regulatory complex subunit 12 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300663, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Drc12provided by RGD
    Official Full Name
    dynein regulatory complex subunit 12 homologprovided by RGD
    Primary source
    RGD:1305351
    See related
    EnsemblRapid:ENSRNOG00000039086 AllianceGenome:RGD:1305351
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc153; RGD1305351
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Orthologous to human DRC12 (dynein regulatory complex subunit 12 homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 66.4) and Brain (RPKM 7.9) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Drc12 in Genome Data Viewer
    Location:
    8q22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (53468344..53481168)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (44576528..44584345)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (48570718..48577856)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene melanoma cell adhesion molecule Neighboring gene Cbl proto-oncogene Neighboring gene NHERF family PDZ scaffold protein 4 Neighboring gene NLR family member X1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109180

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dynein regulatory complex protein 12; coiled-coil domain-containing protein 153
    Names
    coiled-coil domain containing 153

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013953.1 → NP_001013975.1  dynein regulatory complex protein 12

      See identical proteins and their annotated locations for NP_001013975.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089910
      UniProtKB/Swiss-Prot
      Q5FVL4
      UniProtKB/TrEMBL
      A6J3W3
      Related
      ENSRNOP00000056528.3, ENSRNOT00000059776.4
      Conserved Domains (1) summary
      TIGR02168
      Location:28 → 176
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      53468344..53481168
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081050.2 → XP_038936978.1  coiled-coil domain-containing protein 153 isoform X3

      Conserved Domains (1) summary
      pfam14817
      Location:51 → 155
      HAUS5; HAUS augmin-like complex subunit 5

    2. XM_063265104.1 → XP_063121174.1  coiled-coil domain-containing protein 153 isoform X1

      UniProtKB/Swiss-Prot
      Q5FVL4

    3. XM_063265105.1 → XP_063121175.1  coiled-coil domain-containing protein 153 isoform X3

    4. XM_006242913.5 → XP_006242975.1  coiled-coil domain-containing protein 153 isoform X1

      See identical proteins and their annotated locations for XP_006242975.1

      UniProtKB/Swiss-Prot
      Q5FVL4
      UniProtKB/TrEMBL
      A6J3W3
      Conserved Domains (1) summary
      TIGR02168
      Location:28 → 176
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    5. XM_039081049.2 → XP_038936977.1  coiled-coil domain-containing protein 153 isoform X2

      Conserved Domains (1) summary
      PRK04863
      Location:38 → 140
      mukB; chromosome partition protein MukB
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FVL4.1 GenPept UniProtKB/Swiss-Prot:Q5FVL4

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