camk4.L calcium/calmodulin-dependent protein kinase IV L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: camk4.L
Official Full Name: calcium/calmodulin-dependent protein kinase IV L homeolog
Primary source: Xenbase:XB-GENE-5911786
Locus tag: XELAEV_18008011mg
See related: EnsemblRapid:ENSXLAG00005030153 AllianceGenome:Xenbase:XB-GENE-5911786
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: xCaM; camk4; camk4-A
Summary: Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Is expressed in ectoderm; nervous system; sensory system; and visual system. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human CAMK4 (calcium/calmodulin dependent protein kinase IV). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

Location:: chromosome: 1L

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1L	NC_054371.1 (188252010..188339801, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1L	NC_030724.1 (175104426..175192751, complement)

Chromosome 1L - NC_054371.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: calcium/calmodulin-dependent protein kinase IV L homeolog

NP_001079220.1

EC 2.7.11.17

XP_018111325.1

EC 2.7.11.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001085751.1 → NP_001079220.1 calcium/calmodulin-dependent protein kinase IV L homeolog

See identical proteins and their annotated locations for NP_001079220.1

Status: PROVISIONAL

Source sequence(s)

AF316822

UniProtKB/TrEMBL

A0A974E1T3, Q98TZ2

Related

ENSXLAP00005090251.1, ENSXLAT00005091927.1

Conserved Domains (2) summary

cd14085
Location:47 → 339

STKc_CaMKIV; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type IV

pfam00069
Location:51 → 304

Pkinase; Protein kinase domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

188252010..188339801 complement

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GenBank, FASTA, Sequence Viewer (Graphics)