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    MAN2 putative mannitol dehydrogenase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855810, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MAN2
    Official Full Name
    putative mannitol dehydrogenase
    Primary source
    SGD:S000005356
    Locus tag
    YNR073C
    See related
    AllianceGenome:SGD:S000005356; FungiDB:YNR073C; VEuPathDB:YNR073C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables mannitol dehydrogenase activity. Predicted to be involved in mannitol metabolic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MAN2 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (774792..776300, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene aldose 1-epimerase superfamily protein Neighboring gene hexose transporter HXT17 Neighboring gene Aif1p Neighboring gene Cos10p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequencing of a 9.2 kb telomeric fragment from the right arm of Saccharomyces cerevisiae chromosome XIV. Levesque H, et al. Yeast, 1996 Mar 15. PMID 8904342
    2. Hxt13, Hxt15, Hxt16 and Hxt17 from Saccharomyces cerevisiae represent a novel type of polyol transporters. Jordan P, et al. Sci Rep, 2016 Mar 21. PMID 26996892, Free PMC Article
    3. Cdc1p is a Golgi-localized glycosylphosphatidylinositol-anchored protein remodelase. Yang G, et al. Mol Biol Cell, 2020 Dec 15. PMID 33112703, Free PMC Article
    4. Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Katju V, et al. Genome Biol, 2009. PMID 19594930, Free PMC Article
    5. Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis. Mattiazzi Ušaj M, et al. Metallomics, 2015 Sep. PMID 26067383

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables mannitol 2-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mannitol dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mannitol dehydrogenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in mannitol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    putative mannitol dehydrogenase
    NP_014471.3
    • Mannitol dehydrogenase; MAN2 has a paralog, DSF1, that arose from a segmental duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      774792..776300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183250.3 → NP_014471.3  TPA: putative mannitol dehydrogenase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014471.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLI1, P0CX08, P0CX09, P39941
      UniProtKB/TrEMBL
      A6ZSE7, B3LPH1, B3LRV0, B5VH68, C8ZFV0
      Conserved Domains (1) summary
      COG0246
      Location:21 → 498
      MtlD; Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX08.1
    P0CX09.1

    Gene LinkOut

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    Other Literature Sources
    Molecular Biology Databases
    Research Materials