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    KRE9 Kre9p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853265, updated on 9-Dec-2024

    Summary

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    Official Symbol
    KRE9
    Official Full Name
    Kre9p
    Primary source
    SGD:S000003710
    Locus tag
    YJL174W
    See related
    AllianceGenome:SGD:S000003710; FungiDB:YJL174W; VEuPathDB:YJL174W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in (1->6)-beta-D-glucan metabolic process and fungal-type cell wall organization. Located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See KRE9 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (95092..95922)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L17B Neighboring gene Swi3p Neighboring gene Rfa3p Neighboring gene Gly-Xaa carboxypeptidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SKN7, a yeast multicopy suppressor of a mutation affecting cell wall beta-glucan assembly, encodes a product with domains homologous to prokaryotic two-component regulators and to heat shock transcription factors. Brown JL, et al. J Bacteriol, 1993 Nov. PMID 8226633, Free PMC Article
    2. The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9. Dijkgraaf GJ, et al. Yeast, 1996 Jun 15. PMID 8810042
    3. Yeast Skn7p functions in a eukaryotic two-component regulatory pathway. Brown JL, et al. EMBO J, 1994 Nov 1. PMID 7957083, Free PMC Article
    4. Genetic, biochemical, and morphological evidence for the involvement of N-glycosylation in biosynthesis of the cell wall beta1,6-glucan of Saccharomyces cerevisiae. Chavan M, et al. Proc Natl Acad Sci U S A, 2003 Dec 23. PMID 14676317, Free PMC Article
    5. The yeast KRE9 gene encodes an O glycoprotein involved in cell surface beta-glucan assembly. Brown JL, et al. Mol Cell Biol, 1993 Oct. PMID 8413233, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in (1->6)-beta-D-glucan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in (1->6)-beta-D-glucan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in (1->6)-beta-D-glucan metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell wall biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Kre9p
    NP_012361.1
    • Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      95092..95922
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181607.1 → NP_012361.1  TPA: Kre9p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012361.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW14, P39005
      UniProtKB/TrEMBL
      A6ZQF9, B3LPV0, B5VL14, C7GS01, C8ZB45, G2WGK0
      Conserved Domains (2) summary
      pfam10342
      Location:27 → 133
      GPI-anchored; Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
      pfam05390
      Location:173 → 273
      KRE9; Yeast cell wall synthesis protein KRE9/KNH1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P39005.1

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