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    EGT2 Egt2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855389, updated on 9-Dec-2024

    Summary

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    Official Symbol
    EGT2
    Official Full Name
    Egt2p
    Primary source
    SGD:S000005271
    Locus tag
    YNL327W
    See related
    AllianceGenome:SGD:S000005271; FungiDB:YNL327W; VEuPathDB:YNL327W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable cellulase activity. Involved in septum digestion after cytokinesis. Located in cell septum; cellular bud; and cellular bud scar. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See EGT2 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (24048..27173)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene AAA family ATPase peroxin 6 Neighboring gene Mdj2p Neighboring gene palmitoyltransferase PFA3 Neighboring gene phosphatidylinositol-3,5-bisphosphate 5-phosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Biosynthetic pathway of GPI-anchored cell wall mannoproteins in yeast as a potential target for anti-fungal and anti-cancer drugs]. Jigami Y. Nihon Ishinkin Gakkai Zasshi, 2008. PMID 19001750
    2. EGT2 gene transcription is induced predominantly by Swi5 in early G1. Kovacech B, et al. Mol Cell Biol, 1996 Jul. PMID 8668141, Free PMC Article
    3. The localization change of Ybr078w/Ecm33, a yeast GPI-associated protein, from the plasma membrane to the cell wall, affecting the cellular function. Terashima H, et al. FEMS Microbiol Lett, 2003 Jan 21. PMID 12583915
    4. GPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation. Fujita M, et al. J Biol Chem, 2004 Dec 10. PMID 15452134
    5. Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins. Jansen RP, et al. Cell, 1996 Mar 8. PMID 8625407

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables cellulase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in septum digestion after cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell septum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud scar IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Egt2p
    NP_014072.2
    • Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; localizes in birth scars; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      24048..27173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183165.2 → NP_014072.2  TPA: Egt2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014072.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0M0, P42835
      UniProtKB/TrEMBL
      G2WLE4, N1NYC3
      Conserved Domains (1) summary
      NF033849
      Location:695 → 937
      ser_rich_anae_1; serine-rich protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42835.2

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