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    fliS flagellar biosynthesis protein FliS [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946429, updated on 3-Dec-2024

    Summary

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    Official Symbol
    fliS
    Official Full Name
    flagellar biosynthesis protein FliS
    Primary source
    ECOCYC:EG11388
    Locus tag
    b1925
    See related
    ASAP:ABE-0006409
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1924
    Summary
    Flagellar regulon. [More information is available at EcoGene: EG11388]. FliS, along with FliT and FlgN, are cytoplasmic, substrate-specific chaperones of the flagellar export system. [More information is available at EcoCyc: EG11388].
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    Genomic context

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    Sequence:
    NC_000913.3 (2005303..2005713)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene flagellar filament structural protein Neighboring gene flagellar filament capping protein Neighboring gene flagellar biosynthesis protein FliT Neighboring gene alpha-amylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The FliS chaperone selectively binds the disordered flagellin C-terminal D0 domain central to polymerisation. Ozin AJ, et al. FEMS Microbiol Lett, 2003 Feb 28. PMID 12620624
    2. Functional analysis of the flagellar genes in the fliD operon of Salmonella typhimurium. Yokoseki T, et al. Microbiology (Reading), 1995 Jul. PMID 7551038
    3. Escherichia coli flagellar genes as target sites for integration and expression of genetic circuits. Juhas M, et al. PLoS One, 2014. PMID 25350000, Free PMC Article
    4. Negative regulation by fliD, fliS, and fliT of the export of the flagellum-specific anti-sigma factor, FlgM, in Salmonella typhimurium. Yokoseki T, et al. J Bacteriol, 1996 Feb. PMID 8550529, Free PMC Article
    5. Excretion of the anti-sigma factor through a flagellar substructure couples flagellar gene expression with flagellar assembly in Salmonella typhimurium. Kutsukake K. Mol Gen Genet, 1994 Jun 15. PMID 8028576

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. analysis of integration and expression at four candidate loci, fliD, fliS, fliT, and fliY, of the E. coli flagellar region 3a
      Title: Escherichia coli flagellar genes as target sites for integration and expression of genetic circuits.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in bacterial-type flagellum assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in bacterial-type flagellum organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in bacterial-type flagellum-dependent cell motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within bacterial-type flagellum-dependent cell motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    flagellar biosynthesis protein FliS

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2005303..2005713
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416435.1 flagellar biosynthesis protein FliS [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416435.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S0FS48
      Conserved Domains (2) summary
      TIGR00208
      Location:1 → 129
      fliS; flagellar biosynthetic protein FliS
      cd16098
      Location:25 → 45
      FliS; coiled coil [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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