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    fliH flagellar biosynthesis protein FliH [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946456, updated on 3-Dec-2024

    Summary

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    Official Symbol
    fliH
    Official Full Name
    flagellar biosynthesis protein FliH
    Primary source
    ECOCYC:EG11656
    Locus tag
    b1940
    See related
    ASAP:ABE-0006458
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1938; flaAII.3; flaBIII
    Summary
    Characterized primarily in Salmonella. [More information is available at EcoGene: EG11656]. FliH is a cytoplasmic protein which exists as a dimer in solution and forms a stable heterotrimeric complex with FliI, inhibiting its ATPase activity . [More information is available at EcoCyc: EG11656].
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    Genomic context

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    Sequence:
    NC_000913.3 (2015868..2016554)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene flagellar protein FliE Neighboring gene flagellar basal-body MS-ring and collar protein Neighboring gene flagellar motor switch protein FliG Neighboring gene flagellar export ATPase FliI Neighboring gene flagellar biosynthesis protein FliJ Neighboring gene flagellar hook-length control protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteolytic analysis of the FliH/FliI complex, the ATPase component of the type III flagellar export apparatus of Salmonella. Minamino T, et al. J Mol Biol, 2001 Oct 5. PMID 11580247
    2. Intrinsic membrane targeting of the flagellar export ATPase FliI: interaction with acidic phospholipids and FliH. Auvray F, et al. J Mol Biol, 2002 May 10. PMID 12054792, Free PMC Article
    3. Fusions of flagellar operons to lactose genes on a mu lac bacteriophage. Komeda Y. J Bacteriol, 1982 Apr. PMID 7037746, Free PMC Article
    4. Definition of additional flagellar genes in Escherichia coli K12. Komeda Y, et al. Genetics, 1980 Feb. PMID 6993282, Free PMC Article
    5. Gene sequence, overproduction, purification and determination of the wild-type level of the Escherichia coli flagellar switch protein FliG. Roman SJ, et al. Gene, 1993 Oct 29. PMID 8224881

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables cytoskeletal motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in bacterial-type flagellum organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in bacterial-type flagellum-dependent cell motility IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in bacterial-type flagellum-dependent cell motility NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in chemotaxis NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in protein secretion by the type III secretion system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in bacterial-type flagellum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in bacterial-type flagellum NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in bacterial-type flagellum secretion apparatus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of type III protein secretion system complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    flagellar biosynthesis protein FliH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2015868..2016554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416450.2 flagellar biosynthesis protein FliH [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416450.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1V2GD13, A0A7D6J992
      Conserved Domains (1) summary
      PRK05687
      Location:1 → 227
      fliH; flagellar assembly protein FliH
    Nucleotide Protein
    Heading Accession and Version

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