maeB malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: maeB
Official Full Name: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))
Primary source: ECOCYC:G7293
Locus tag: b2463
See related: ASAP:ABE-0008111
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK2458; ypfF
Summary: Acetyl-CoA and cAMP are allosteric inhibitors. [More information is available at EcoGene: EG14193]. There are two malic enzymes in Escherichia coli, one NAD-linked (encoded by the maeA gene) and the other NADP-linked (encoded by the maeB gene) . [More information is available at EcoCyc: G7293].
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

These results indicated that MaeB was important for NADPH production for bacterial growth on acetate.
Title: Biochemical properties and physiological roles of NADP-dependent malic enzyme in Escherichia coli.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IDA Inferred from Direct Assay more info	PubMed
enables malate dehydrogenase (decarboxylating) (NADP+) activity	IDA Inferred from Direct Assay more info	PubMed
enables malate dehydrogenase (decarboxylating) (NADP+) activity	IEA Inferred from Electronic Annotation more info
enables malate dehydrogenase (decarboxylating) (NADP+) activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables malic enzyme activity	IEA Inferred from Electronic Annotation more info
enables malolactic enzyme activity	IDA Inferred from Direct Assay more info	PubMed
enables manganese ion binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxaloacetate decarboxylase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in malate metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	HDA more info	PubMed

Preferred Names: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))

NP_416958.1

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The following sections contain reference sequences that belong to a specific genome build. Explain