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    purN phosphoribosylglycinamide formyltransferase 1 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946973, updated on 3-Dec-2024

    Summary

    Official Symbol
    purN
    Official Full Name
    phosphoribosylglycinamide formyltransferase 1
    Primary source
    ECOCYC:EG10799
    Locus tag
    b2500
    See related
    ASAP:ABE-0008232
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ade; ade(c); ECK2496
    Summary
    Based on polarity studies, the expression of the purN gene originates from the purM control region and thus forms a purMN operon. [More information is available at EcoCyc: EG10799].
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    Genomic context

    Sequence:
    NC_000913.3 (2622234..2622872)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene uracil:H(+) symporter UraA Neighboring gene uracil phosphoribosyltransferase Neighboring gene phosphoribosylformylglycinamide cyclo-ligase Neighboring gene polyphosphate kinase Neighboring gene exopolyphosphatase

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoribosylglycinamide formyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphoribosylglycinamide formyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphoribosylglycinamide formyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in 'de novo' IMP biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in 'de novo' IMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in purine nucleotide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    phosphoribosylglycinamide formyltransferase 1
    NP_416995.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2622234..2622872
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416995.1 phosphoribosylglycinamide formyltransferase 1 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416995.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376SB76, Q9F6H5
      Conserved Domains (1) summary
      PRK05647
      Location:1199
      purN; phosphoribosylglycinamide formyltransferase; Reviewed