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    aaeA aromatic carboxylic acid efflux pump membrane fusion protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947748, updated on 3-Dec-2024

    Summary

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    Official Symbol
    aaeA
    Official Full Name
    aromatic carboxylic acid efflux pump membrane fusion protein
    Primary source
    ECOCYC:G7686
    Locus tag
    b3241
    See related
    ASAP:ABE-0010631
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3230; yhcQ
    Summary
    AaeAB also exports related aromatic carboxylic acids. [More information is available at EcoGene: EG12823]. The aaeA and aaeB genes are members of the aaeXAB operon. [More information is available at EcoCyc: G7686].
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    Genomic context

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    Sequence:
    NC_000913.3 (3388194..3389126, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative barnase inhibitor Neighboring gene aromatic carboxylic acid efflux pump subunit AaeB Neighboring gene DUF1656 domain-containing protein AaeX Neighboring gene DNA-binding transcriptional activator AaeR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel ubiquitous family of putative efflux transporters. Harley KT, et al. J Mol Microbiol Biotechnol, 2000 Apr. PMID 10939244
    2. Role of the rapA gene in controlling antibiotic resistance of Escherichia coli biofilms. Lynch SV, et al. Antimicrob Agents Chemother, 2007 Oct. PMID 17664315, Free PMC Article
    3. Characterization of the Escherichia coli AaeAB efflux pump: a metabolic relief valve? Van Dyk TK, et al. J Bacteriol, 2004 Nov. PMID 15489430, Free PMC Article
    4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
    5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within carboxylic acid transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    aromatic carboxylic acid efflux pump membrane fusion protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3388194..3389126 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417708.1 aromatic carboxylic acid efflux pump membrane fusion protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417708.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A418GE59, A0A8S7CET2
      Conserved Domains (1) summary
      PRK10559
      Location:1 → 310
      PRK10559; p-hydroxybenzoic acid efflux pump subunit AaeA
    Nucleotide Protein
    Heading Accession and Version

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