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    prmA ribosomal protein L11 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947708, updated on 3-Dec-2024

    Summary

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    Official Symbol
    prmA
    Official Full Name
    ribosomal protein L11 methyltransferase
    Primary source
    ECOCYC:EG11497
    Locus tag
    b3259
    See related
    ASAP:ABE-0010697
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3246; prm-1; yhdI
    Summary
    PrmA is the methyltransferase responsible for the multiple methylation of ribosomal protein L11. prmA mutants are deficient in the methylation of ribosomal protein L11 . [More information is available at EcoCyc: EG11497].
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    Genomic context

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    Sequence:
    NC_000913.3 (3409070..3409951)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene biotin carboxylase Neighboring gene DUF997 domain-containing protein YhdT Neighboring gene pantothenate:Na(+) symporter Neighboring gene tRNA-dihydrouridine synthase B Neighboring gene DNA-binding transcriptional dual regulator Fis

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and properties of a ribosomal protein methylase from Eschericha coli Q13. Chang FN, et al. Biochemistry, 1975 Nov 4. PMID 241395
    2. Genetics of ribosomal protein methylation in Escherichia coli. I. A mutant deficient in methylation of protein L11. Colson C. Mol Gen Genet, 1977 Jul 20. PMID 331082
    3. Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases. Bujnicki JM. Acta Microbiol Pol, 2000. PMID 10997488
    4. N-Trimethylalanine, a novel blocking group, found in E. coli ribosomal protein L11. Lederer F, et al. Biochem Biophys Res Commun, 1977 Jul 25. PMID 332162
    5. Genetics of ribosomal protein methylation in Escherichia coli. III. Map position of two genes, prmA and prmB, governing methylation of proteins L11 and L3. Colson C, et al. Mol Gen Genet, 1979 Feb 1. PMID 372746

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
      Title: Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables N-terminal protein N-methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables histone methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-lysine N-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribosomal protein L11 methyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3409070..3409951
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417725.1 ribosomal protein L11 methyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417725.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T6QD37
      Conserved Domains (1) summary
      TIGR00406
      Location:3 → 286
      prmA; ribosomal protein L11 methyltransferase
    Nucleotide Protein
    Heading Accession and Version

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