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    nirB nitrite reductase (NADH) large subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947868, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nirB
    Official Full Name
    nitrite reductase (NADH) large subunit
    Primary source
    ECOCYC:EG10653
    Locus tag
    b3365
    See related
    ASAP:ABE-0011003
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3353
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    Genomic context

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    Sequence:
    NC_000913.3 (3494011..3496554)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase A Neighboring gene putative transporter TsgA Neighboring gene nitrite reductase (NADH) small subunit Neighboring gene nitrite transporter NirC Neighboring gene siroheme synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of the NADH-dependent nitrite reductase, Nir, from Escherichia coli in fermentative ammonification. Wang X, et al. Arch Microbiol, 2019 May. PMID 30406295
    2. Regulation by nucleoid-associated proteins at the Escherichia coli nir operon promoter. Browning DF, et al. J Bacteriol, 2008 Nov. PMID 18757534, Free PMC Article
    3. Clustering as a Means To Control Nitrate Respiration Efficiency and Toxicity in Escherichia coli. Bulot S, et al. mBio, 2019 Oct 22. PMID 31641084, Free PMC Article
    4. Purification and properties of nitrite reductase from Escherichia coli K12. Coleman KJ, et al. Biochem J, 1978 Nov 1. PMID 217342, Free PMC Article
    5. Molecular genetic analysis of an FNR-dependent anaerobically inducible Escherichia coli promoter. Bell AI, et al. Mol Microbiol, 1990 Oct. PMID 2077359

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitrite reductase NADH activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nitrite reductase NADH activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitrite reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NADH oxidation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in fermentation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nitrate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nitrate assimilation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nitrite reductase complex [NAD(P)H] IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nitrite reductase (NADH) large subunit
    NP_417824.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3494011..3496554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417824.1 nitrite reductase (NADH) large subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417824.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FVP2, A0A8S7BDP9, A0A8S7I281, A0A8S7MUN5, A0AAN3TSJ6
      Conserved Domains (1) summary
      PRK14989
      Location:1 → 847
      PRK14989; nitrite reductase subunit NirD; Provisional
    Nucleotide Protein
    Heading Accession and Version

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