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    xylA xylose isomerase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948141, updated on 3-Dec-2024

    Summary

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    Official Symbol
    xylA
    Official Full Name
    xylose isomerase
    Primary source
    ECOCYC:EG11074
    Locus tag
    b3565
    See related
    ASAP:ABE-0011639
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3554
    Summary
    Xylose isomerase catalyzes the first reaction in the catabolism of D-xylose . [More information is available at EcoCyc: EG11074].
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    Genomic context

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    Sequence:
    NC_000913.3 (3729443..3730765, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF05360 family inner membrane protein YiaB Neighboring gene xylulokinase Neighboring gene ncRNA Neighboring gene xylose ABC transporter periplasmic binding protein Neighboring gene xylose ABC transporter ATP binding subunit Neighboring gene xylose ABC transporter membrane subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fluorescent properties of the Escherichia coli D-xylose isomerase active site. Jamieson AC, et al. Protein Eng, 1992 Apr. PMID 1409543
    2. Sequence analysis of D-xylose isomerase gene from Escherichia coli. Hou YM, et al. Chin J Biotechnol, 1990. PMID 2132127
    3. Influence of divalent cations on the structural thermostability and thermal inactivation kinetics of class II xylose isomerases. Epting KL, et al. FEBS J, 2005 Mar. PMID 15752361
    4. [Cloning of Escherichia coli K12 xylose isomerase (glucose isomerase) and studying the enzymatic properties of its expression product]. Rozanov AS, et al. Prikl Biokhim Mikrobiol, 2009 Jan-Feb. PMID 19235507
    5. Amplification of D-xylose and D-glucose isomerase activities in Escherichia coli by gene cloning. Wovcha MG, et al. Appl Environ Microbiol, 1983 Apr. PMID 6344793, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables xylose isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables xylose isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables xylose isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables xylose isomerase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-xylose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within D-xylose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in D-xylose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    xylose isomerase
    NP_418022.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3729443..3730765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418022.1 xylose isomerase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418022.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A826IYQ1
      Conserved Domains (1) summary
      PRK05474
      Location:3 → 439
      PRK05474; xylose isomerase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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