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    gmk guanylate kinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948163, updated on 3-Dec-2024

    Summary

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    Official Symbol
    gmk
    Official Full Name
    guanylate kinase
    Primary source
    ECOCYC:EG10965
    Locus tag
    b3648
    See related
    ASAP:ABE-0011930
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3638; spoR
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    Genomic context

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    Sequence:
    NC_000913.3 (3821428..3822051)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA damage-inducible protein D Neighboring gene PF03458 family inner membrane protein YicG Neighboring gene DNA ligase B Neighboring gene RNA polymerase subunit omega Neighboring gene bifunctional (p)ppGpp synthase/hydrolase SpoT

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G. Hible G, et al. Biochimie, 2006 Sep. PMID 16690197
    2. Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase. Hible G, et al. J Mol Biol, 2005 Oct 7. PMID 16140325
    3. A novel Escherichia coli strain allows functional analysis of guanylate kinase drug resistance and sensitivity. Stolworthy TS, et al. Anal Biochem, 2003 Nov 1. PMID 14705778
    4. Purification and properties of guanylate kinase from Escherichia coli. Oeschger MP, et al. J Biol Chem, 1966 Nov 25. PMID 5333666
    5. Guanylate kinase of Escherichia coli K-12. Gentry D, et al. J Biol Chem, 1993 Jul 5. PMID 8390989

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanylate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanylate kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables guanylate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GDP metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in GMP metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in purine nucleotide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanylate kinase
    NP_418105.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3821428..3822051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418105.1 guanylate kinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418105.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5C9ABX0, A0A7A3JA91
      Conserved Domains (1) summary
      PRK00300
      Location:1 → 206
      gmk; guanylate kinase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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