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    rhaS DNA-binding transcriptional activator RhaS [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948397, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rhaS
    Official Full Name
    DNA-binding transcriptional activator RhaS
    Primary source
    ECOCYC:EG10843
    Locus tag
    b3905
    See related
    ASAP:ABE-0012745
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3898; rhaC2
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    Genomic context

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    Sequence:
    NC_000913.3 (4097736..4098572)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene rhamnulose-1-phosphate aldolase Neighboring gene L-rhamnose isomerase Neighboring gene rhamnulokinase Neighboring gene DNA-binding transcriptional activator RhaR Neighboring gene rhamnose/lyxose:H(+) symporter Neighboring gene superoxide dismutase (Mn)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic evidence that transcription activation by RhaS involves specific amino acid contacts with sigma 70. Bhende PM, et al. J Bacteriol, 2000 Sep. PMID 10940041, Free PMC Article
    2. Linker regions of the RhaS and RhaR proteins. Kolin A, et al. J Bacteriol, 2007 Jan. PMID 17071764, Free PMC Article
    3. Transcription from the rha operon psr promoter. Tobin JF, et al. J Mol Biol, 1990 Jan 5. PMID 1688950
    4. Purification and properties of RhaR, the positive regulator of the L-rhamnose operons of Escherichia coli. Tobin JF, et al. J Mol Biol, 1990 Jan 5. PMID 2405166
    5. Amino acid-DNA contacts by RhaS: an AraC family transcription activator. Bhende PM, et al. J Bacteriol, 1999 Sep. PMID 10464186, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results indicate that RhaS negative autoregulation involves RhaS competition with RhaR for binding to the RhaR binding site at rhaSR.
      Title: The AraC/XylS family activator RhaS negatively autoregulates rhaSR expression by preventing cyclic AMP receptor protein activation.
    2. Results show that DNA-binding domains of RhaS (RhaS-CTD)contains all of the determinants necessary for transcription activation by RhaS.
      Title: Transcription activation by the DNA-binding domain of the AraC family protein RhaS in the absence of its effector-binding domain.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of primary metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rhamnose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional activator RhaS

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4097736..4098572
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418341.1 DNA-binding transcriptional activator RhaS [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418341.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377B6B2
      Conserved Domains (1) summary
      PRK13503
      Location:1 → 278
      PRK13503; HTH-type transcriptional activator RhaS
    Nucleotide Protein
    Heading Accession and Version

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