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    nfrA exopolysaccharide secretion system outer membrane protein NfrA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944741, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nfrA
    Official Full Name
    exopolysaccharide secretion system outer membrane protein NfrA
    Primary source
    ECOCYC:EG11740
    Locus tag
    b0568
    See related
    ASAP:ABE-0001939
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0560
    Summary
    Isolation of spontaneous N4 bacteriophage-resistant mutants of Escherichia coli K-12 strain SC1100, cloning of the affected genes, and subsequent complementation experiments revealed that nfrA is important in N4 adsorption. [More information is available at EcoCyc: EG11740].
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    Genomic context

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    Sequence:
    NC_000913.3 (587982..590954, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator EnvY Neighboring gene putative exopolysaccharide secretion system auxiliary component Neighboring gene cyclic di-3',5'-guanylate-activated glycosyltransferase Neighboring gene sensor histidine kinase CusS Neighboring gene DNA-binding transcriptional activator CusR Neighboring gene copper/silver export system outer membrane channel

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Biochemical bases for the effect of combining kanamycin and nitrofuran resistance genes in Escherichia coli cells]. Morozov GI, et al. Mol Gen Mikrobiol Virusol, 1994 Mar-Apr. PMID 8183300
    2. Genetic analysis of bacteriophage N4 adsorption. Kiino DR, et al. J Bacteriol, 1989 Sep. PMID 2670887, Free PMC Article
    3. The tail sheath of bacteriophage N4 interacts with the Escherichia coli receptor. McPartland J, et al. J Bacteriol, 2009 Jan. PMID 19011026, Free PMC Article
    4. Two overlapping genes encoding membrane proteins required for bacteriophage N4 adsorption. Kiino DR, et al. J Bacteriol, 1993 Nov. PMID 8226649, Free PMC Article
    5. A Novel Locally c-di-GMP-Controlled Exopolysaccharide Synthase Required for Bacteriophage N4 Infection of Escherichia coli. Junkermeier EH, et al. mBio, 2021 Dec 21. PMID 34903052, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Viral gp65 interacts with Escherichia coli outer membrane receptor, NfrA.
      Title: The tail sheath of bacteriophage N4 interacts with the Escherichia coli receptor.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in receptor-mediated virion attachment to host cell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within receptor-mediated virion attachment to host cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in secretion by cell IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    exopolysaccharide secretion system outer membrane protein NfrA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      587982..590954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415100.1 exopolysaccharide secretion system outer membrane protein NfrA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415100.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FQI0
      Conserved Domains (2) summary
      PRK09782
      Location:4 → 990
      PRK09782; bacteriophage N4 receptor, outer membrane subunit; Provisional
      sd00006
      Location:611 → 641
      TPR; TPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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