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    abgT p-aminobenzoyl glutamate:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945912, updated on 3-Dec-2024

    Summary

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    Official Symbol
    abgT
    Official Full Name
    p-aminobenzoyl glutamate:H(+) symporter
    Primary source
    ECOCYC:EG12853
    Locus tag
    b1336
    See related
    ASAP:ABE-0004488
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1332; ydaH
    Summary
    Artificial expression of abgT allows the uptake of p-aminobenzoyl-glutamate (Hussein, 1998; Carter, 2007). abgAB expression catalyzes the p-aminobenzoyl-glutamate assimilation to feed p-aminobenzoate auxotrophs (Carter, 2007). [More information is available at EcoGene: EG12853]. The AbgT protein is a possible p-aminobenzoyl-glutamate transporter. [More information is available at EcoCyc: EG12853].
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    Genomic context

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    Sequence:
    NC_000913.3 (1400247..1401773, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator FNR Neighboring gene methylated-DNA--[protein]-cysteine S-methyltransferase Neighboring gene p-aminobenzoyl-glutamate hydrolase subunit B Neighboring gene p-aminobenzoyl-glutamate hydrolase subunit A Neighboring gene putative LysR-type DNA-binding transcriptional regulator AbgR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli. Potter PM, et al. Nucleic Acids Res, 1987 Nov 25. PMID 2825131, Free PMC Article
    2. Escherichia coli abg genes enable uptake and cleavage of the folate catabolite p-aminobenzoyl-glutamate. Carter EL, et al. J Bacteriol, 2007 May. PMID 17307853, Free PMC Article
    3. Characterization of mutations that allow p-aminobenzoyl-glutamate utilization by Escherichia coli. Hussein MJ, et al. J Bacteriol, 1998 Dec. PMID 9829935, Free PMC Article
    4. Domain structure and pore loops in the 2-hydroxycarboxylate transporter family. Lolkema JS. J Mol Microbiol Biotechnol, 2006. PMID 17114896
    5. Sequence and hydropathy profile analysis of two classes of secondary transporters. Lolkema JS, et al. Mol Membr Biol, 2005 May-Jun. PMID 16096261

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables secondary active p-aminobenzoyl-glutamate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables secondary active p-aminobenzoyl-glutamate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables secondary active p-aminobenzoyl-glutamate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables secondary active transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in p-aminobenzoyl-glutamate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in p-aminobenzoyl-glutamate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within p-aminobenzoyl-glutamate transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    p-aminobenzoyl glutamate:H(+) symporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1400247..1401773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415852.2 p-aminobenzoyl glutamate:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415852.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EDK7, A0A8S7NQQ6
      Conserved Domains (1) summary
      PRK11339
      Location:1 → 508
      abgT; putative aminobenzoyl-glutamate transporter; Provisional
    Nucleotide Protein
    Heading Accession and Version

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