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    recT recombinase RecT [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945917, updated on 17-Dec-2024

    Summary

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    Official Symbol
    recT
    Official Full Name
    recombinase RecT
    Primary source
    ECOCYC:EG11899
    Locus tag
    b1349
    See related
    ASAP:ABE-0004529
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1346
    Summary
    RecT still functions without RecE, less efficiently, thus it a short homology recombinase, useful for recombineering. recT is activated by the sbcA mutation. [More information is available at EcoGene: EG11899]. The Rac prophage of Escherichia coli encodes two proteins of the ATP-independent RecE recombination pathway involved in homologous pairing and strand exchange. [More information is available at EcoCyc: EG11899].
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    Genomic context

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    Sequence:
    NC_000913.3 (1413984..1414793, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene excisionase Neighboring gene double-strand break reduction protein Neighboring gene ncRNA Neighboring gene endodeoxyribonuclease toxin RalR Neighboring gene exonuclease VIII, ds DNA exonuclease, 5' --> 3' specific Neighboring gene protein RacC Neighboring gene zinc-binding protein Neighboring gene inhibitor of FtsZ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein. Hall SD, et al. Proc Natl Acad Sci U S A, 1994 Apr 12. PMID 8159725, Free PMC Article
    2. Electron microscopic visualization of RecT protein and its complexes with DNA. Thresher RJ, et al. J Mol Biol, 1995 Dec 1. PMID 7490755
    3. Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA. Hall SD, et al. J Bacteriol, 1993 Jan. PMID 8416902, Free PMC Article
    4. Homologous pairing proteins encoded by the Escherichia coli recE and recT genes. Kolodner R, et al. Mol Microbiol, 1994 Jan. PMID 8145642
    5. Involvement of RecE exonuclease and RecT annealing protein in DNA double-strand break repair by homologous recombination. Kusano K, et al. Gene, 1994 Jan 28. PMID 8125297

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA duplex unwinding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-DNA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    recombinase RecT

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1413984..1414793 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415865.1 recombinase RecT [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415865.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A829L8L9, A0AAN3M814
      Conserved Domains (1) summary
      PRK09846
      Location:8 → 269
      recT; recombination protein RecT
    Nucleotide Protein
    Heading Accession and Version

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