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    phnK carbon-phosphorus lyase subunit PhnK [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948611, updated on 3-Dec-2024

    Summary

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    Official Symbol
    phnK
    Official Full Name
    carbon-phosphorus lyase subunit PhnK
    Primary source
    ECOCYC:EG10720
    Locus tag
    b4097
    See related
    ASAP:ABE-0013424
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4090
    Summary
    Phosphonate utilization is cryptic in K-12. [More information is available at EcoGene: EG10720]. phnK is a member of the 14-gene phnCDEFGHIJKLMNOP operon which is involved in phosphonate uptake and metabolism and is a member of the phosphate regulon . [More information is available at EcoCyc: EG10720].
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    Genomic context

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    Sequence:
    NC_000913.3 (4318006..4318764, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene aminoalkylphosphonate N-acetyltransferase Neighboring gene ribose 1,5-bisphosphate phosphokinase Neighboring gene RPnTP hydrolase Neighboring gene methylphosphonate degradation complex subunit PhnL Neighboring gene carbon-phosphorus lyase core complex subunit PhnJ Neighboring gene carbon-phosphorus lyase core complex subunit PhnI Neighboring gene carbon-phosphorus lyase core complex subunit PhnH Neighboring gene carbon-phosphorus lyase core complex subunit PhnG

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structures of the Carbon-Phosphorus Lyase Complex Reveal the Binding Mode of the NBD-like PhnK. Yang K, et al. Structure, 2016 Jan 5. PMID 26724995, Free PMC Article
    2. Five phosphonate operon gene products as components of a multi-subunit complex of the carbon-phosphorus lyase pathway. Jochimsen B, et al. Proc Natl Acad Sci U S A, 2011 Jul 12. PMID 21705661, Free PMC Article
    3. Phosphate-independent expression of the carbon-phosphorus lyase activity of Escherichia coli. Yakovleva GM, et al. Appl Microbiol Biotechnol, 1998 May. PMID 9650256
    4. Intermediates in the transformation of phosphonates to phosphate by bacteria. Kamat SS, et al. Nature, 2011 Nov 16. PMID 22089136, Free PMC Article
    5. Genes for phosphonate biodegradation in Escherichia coli. Wanner BL. SAAS Bull Biochem Biotechnol, 1992 Jan. PMID 1368181

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in organic phosphonate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within organic phosphonate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in organic phosphonate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in organic phosphonate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in peptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of carbon phosphorus lyase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of carbon phosphorus lyase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carbon-phosphorus lyase subunit PhnK

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4318006..4318764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026282.1 carbon-phosphorus lyase subunit PhnK [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026282.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376ME90
      Conserved Domains (1) summary
      PRK11701
      Location:1 → 252
      phnK; phosphonate C-P lyase system protein PhnK; Provisional
    Nucleotide Protein
    Heading Accession and Version

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