U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    phnJ carbon-phosphorus lyase core complex subunit PhnJ [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948606, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    phnJ
    Official Full Name
    carbon-phosphorus lyase core complex subunit PhnJ
    Primary source
    ECOCYC:EG10719
    Locus tag
    b4098
    See related
    ASAP:ABE-0013426
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4091
    Summary
    Phosphonate utilization is cryptic in K-12. [More information is available at EcoGene: EG10719]. PhnJ appears to be a component of a carbon-phosphorous lyase enzyme. phnJis part of an operon that is phosphate starvation-inducible and required for use of phosphonate and phosphite as phosphorous sources . [More information is available at EcoCyc: EG10719].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4318761..4319606, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene aminoalkylphosphonate N-acetyltransferase Neighboring gene ribose 1,5-bisphosphate phosphokinase Neighboring gene RPnTP hydrolase Neighboring gene methylphosphonate degradation complex subunit PhnL Neighboring gene carbon-phosphorus lyase subunit PhnK Neighboring gene carbon-phosphorus lyase core complex subunit PhnI Neighboring gene carbon-phosphorus lyase core complex subunit PhnH Neighboring gene carbon-phosphorus lyase core complex subunit PhnG Neighboring gene putative transcriptional regulator PhnF

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Amstrup SK, et al. Nat Commun, 2023 Feb 22. PMID 36813778, Free PMC Article
    2. Subunit Interactions within the Carbon-Phosphorus Lyase Complex from Escherichia coli. Ren Z, et al. Biochemistry, 2015 Jun 2. PMID 25954983, Free PMC Article
    3. Five phosphonate operon gene products as components of a multi-subunit complex of the carbon-phosphorus lyase pathway. Jochimsen B, et al. Proc Natl Acad Sci U S A, 2011 Jul 12. PMID 21705661, Free PMC Article
    4. Mapping and molecular cloning of the phn (psiD) locus for phosphonate utilization in Escherichia coli. Wanner BL, et al. J Bacteriol, 1990 Mar. PMID 2155195, Free PMC Article
    5. Phosphate-independent expression of the carbon-phosphorus lyase activity of Escherichia coli. Yakovleva GM, et al. Appl Microbiol Biotechnol, 1998 May. PMID 9650256

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
      Title: Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in organic phosphonate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within organic phosphonate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in organic phosphonate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in organic phosphonate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of carbon phosphorus lyase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of carbon phosphorus lyase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    carbon-phosphorus lyase core complex subunit PhnJ
    NP_418522.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4318761..4319606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418522.1 carbon-phosphorus lyase core complex subunit PhnJ [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418522.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376CVE8
      Conserved Domains (1) summary
      COG3627
      Location:1 → 277
      PhnJ; Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase [Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.