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    treR DNA-binding transcriptional repressor TreR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948760, updated on 3-Dec-2024

    Summary

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    Official Symbol
    treR
    Official Full Name
    DNA-binding transcriptional repressor TreR
    Primary source
    ECOCYC:EG12202
    Locus tag
    b4241
    See related
    ASAP:ABE-0013875
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4236
    Summary
    "Trehalose repressor," TreR, acts as a repressor of operons involved in fucose transport and degradation under osmotic stress . [More information is available at EcoCyc: EG12202].
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    Genomic context

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    Sequence:
    NC_000913.3 (4466299..4467246, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene trehalose-6-phosphate hydrolase Neighboring gene trehalose-specific PTS enzyme IIBC component Neighboring gene leader peptide MgtL Neighboring gene Mg(2(+)) importing P-type ATPase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Saturation transfer difference NMR reveals functionally essential kinetic differences for a sugar-binding repressor protein. Pérez-Victoria I, et al. Chem Commun (Camb), 2009 Oct 21. PMID 19787122
    2. Characterization of a cytoplasmic trehalase of Escherichia coli. Horlacher R, et al. J Bacteriol, 1996 Nov. PMID 8892826, Free PMC Article
    3. The repression of trehalose transport and metabolism in Escherichia coli by high osmolarity is mediated by trehalose-6-phosphate phosphatase. Klein W, et al. Res Microbiol, 1991 May. PMID 1651549
    4. Characterization of TreR, the major regulator of the Escherichia coli trehalose system. Horlacher R, et al. J Biol Chem, 1997 May 16. PMID 9148912
    5. Novel mode of transcription regulation of divergently overlapping promoters by PhoP, the regulator of two-component system sensing external magnesium availability. Yamamoto K, et al. Mol Microbiol, 2002 Jul. PMID 12123454

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in trehalose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional repressor TreR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4466299..4467246 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418662.1 DNA-binding transcriptional repressor TreR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418662.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376JUB0, A0A5B9AML6, A0A8H9SH52, A0A8S7AXN2, A0A8S7XZ36
      Conserved Domains (1) summary
      PRK09492
      Location:1 → 315
      treR; HTH-type transcriptional regulator TreR
    Nucleotide Protein
    Heading Accession and Version

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