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    ppdD prepilin-type N-terminal cleavage/methylation domain-containing protein PpdD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945817, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ppdD
    Official Full Name
    prepilin-type N-terminal cleavage/methylation domain-containing protein PpdD
    Primary source
    ECOCYC:EG12107
    Locus tag
    b0108
    See related
    ASAP:ABE-0000372
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0107
    Summary
    ppdD has been demonstrated to have a CRP-S promoter co-regulated by both Crp and Sxy (Cameron, 2006). [More information is available at EcoGene: EG12107]. ppdD encodes a putative major type IV pilin but was shown to not be expressed in Escherichia coli. [More information is available at EcoCyc: EG12107].
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    Genomic context

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    Sequence:
    NC_000913.3 (117109..117549, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene GMP reductase Neighboring gene inner membrane protein HofC Neighboring gene T2SSE family protein Neighboring gene quinolinate phosphoribosyltransferase (decarboxylating) Neighboring gene 1,6-anhydro-N-acetylmuramoyl-L-alanine amidase Neighboring gene protein AmpE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus. Bardiaux B, et al. Structure, 2019 Jul 2. PMID 31056419, Free PMC Article
    2. Pilus formation and protein secretion by the same machinery in Escherichia coli. Sauvonnet N, et al. EMBO J, 2000 May 15. PMID 10811613, Free PMC Article
    3. Transforming DNA uptake gene orthologs do not mediate spontaneous plasmid transformation in Escherichia coli. Sun D, et al. J Bacteriol, 2009 Feb. PMID 19011021, Free PMC Article
    4. PpdD type IV pilin of Escherichia coli K-12 can Be assembled into pili in Pseudomonas aeruginosa. Sauvonnet N, et al. J Bacteriol, 2000 Feb. PMID 10633126, Free PMC Article
    5. Escherichia coli contains a set of genes homologous to those involved in protein secretion, DNA uptake and the assembly of type-4 fimbriae in other bacteria. Whitchurch CB, et al. Gene, 1994 Dec 2. PMID 7959070

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The molecular structure of the periplasmic domain of PpdD has been defined.
      Title: Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in type IV pilus-dependent motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in pilus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in type IV pilus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    prepilin-type N-terminal cleavage/methylation domain-containing protein PpdD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      117109..117549 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414650.1 prepilin-type N-terminal cleavage/methylation domain-containing protein PpdD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414650.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1N2J3
      Conserved Domains (1) summary
      PRK10574
      Location:1 → 146
      PRK10574; putative major pilin subunit; Provisional
    Nucleotide Protein
    Heading Accession and Version

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