U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pdeB c-di-GMP phosphodiesterase PdeB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948951, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    pdeB
    Official Full Name
    c-di-GMP phosphodiesterase PdeB
    Primary source
    ECOCYC:G6252
    Locus tag
    b0457
    See related
    ASAP:ABE-0001584
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0451; ylaB
    Summary
    YlaB has a C-terminal putative cyclic-di-GMP phosphodiesterase EAL domain. [More information is available at EcoGene: EG14237]. YlaB is an inner membrane protein with two predicted transmembrane domains. [More information is available at EcoCyc: G6252].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (477067..478617, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DUF1428 domain-containing protein YbaA Neighboring gene putative inner membrane protein Neighboring gene maltose O-acetyltransferase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Expression and Genetic Activation of Cyclic Di-GMP-Specific Phosphodiesterases in Escherichia coli. Reinders A, et al. J Bacteriol, 2016 Feb 1. PMID 26553851, Free PMC Article
    2. Transposition is modulated by a diverse set of host factors in Escherichia coli and is stimulated by nutritional stress. Twiss E, et al. Mol Microbiol, 2005 Sep. PMID 16135227
    3. Transmembrane redox control and proteolysis of PdeC, a novel type of c-di-GMP phosphodiesterase. Herbst S, et al. EMBO J, 2018 Apr 13. PMID 29514851, Free PMC Article
    4. Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli. Sommerfeldt N, et al. Microbiology (Reading), 2009 Apr. PMID 19332833
    5. C-di-GMP: the dawning of a novel bacterial signalling system. Römling U, et al. Mol Microbiol, 2005 Aug. PMID 16045609

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables cyclic-guanylate-specific phosphodiesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cyclic-guanylate-specific phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclic-guanylate-specific phosphodiesterase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    c-di-GMP phosphodiesterase PdeB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      477067..478617 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414990.2 c-di-GMP phosphodiesterase PdeB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414990.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T6A0I0
      Conserved Domains (1) summary
      COG4943
      Location:1 → 516
      YjcC; Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.