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    tomB Hha toxicity modulator TomB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945106, updated on 3-Dec-2024

    Summary

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    Official Symbol
    tomB
    Official Full Name
    Hha toxicity modulator TomB
    Primary source
    ECOCYC:EG12429
    Locus tag
    b0461
    See related
    ASAP:ABE-0001596
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0455; ybaJ
    Summary
    Induced during biofilm formation. [More information is available at EcoGene: EG12429]. The tomB-hha operon may encode an antitoxin-toxin module. [More information is available at EcoCyc: EG12429].
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    Genomic context

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    Sequence:
    NC_000913.3 (480334..480708, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene maltose O-acetyltransferase Neighboring gene hemolysin expression-modulating protein Hha Neighboring gene multidrug efflux pump RND permease AcrB Neighboring gene multidrug efflux pump membrane fusion lipoprotein AcrA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An oxygen-sensitive toxin-antitoxin system. Marimon O, et al. Nat Commun, 2016 Dec 8. PMID 27929062, Free PMC Article
    2. The hha gene modulates haemolysin expression in Escherichia coli. Nieto JM, et al. Mol Microbiol, 1991 May. PMID 1956303
    3. Hha, YbaJ, and OmpA regulate Escherichia coli K12 biofilm formation and conjugation plasmids abolish motility. Barrios AF, et al. Biotechnol Bioeng, 2006 Jan 5. PMID 16317765
    4. Protein translation and cell death: the role of rare tRNAs in biofilm formation and in activating dormant phage killer genes. García-Contreras R, et al. PLoS One, 2008 Jun 11. PMID 18545668, Free PMC Article
    5. Transcriptional response of Escherichia coli to external copper. Yamamoto K, et al. Mol Microbiol, 2005 Apr. PMID 15773991

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within single-species biofilm formation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Hha toxicity modulator TomB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      480334..480708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414994.1 Hha toxicity modulator TomB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414994.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1MYL7
      Conserved Domains (1) summary
      PRK10667
      Location:1 → 122
      PRK10667; Hha toxicity modulator TomB
    Nucleotide Protein
    Heading Accession and Version

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