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    ybdK putative glutamate--cysteine ligase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947246, updated on 17-Dec-2024

    Summary

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    Official Symbol
    ybdK
    Official Full Name
    putative glutamate--cysteine ligase 2
    Primary source
    ECOCYC:G6326
    Locus tag
    b0581
    See related
    ASAP:ABE-0001992
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0573
    Summary
    AFMB Structural Genomics target Number 91 (http://afmb.cnrs-mrs.fr/article171.html. [More information is available at EcoGene: EG13644]. YbdK catalyzes the ligation of glutamate with cysteine at a slow catalytic rate. [More information is available at EcoCyc: G6326].
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    Genomic context

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    Sequence:
    NC_000913.3 (606265..607383, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF04237 family protein YbdF Neighboring gene DUF1158 domain-containing protein YbdJ Neighboring gene ncRNA Neighboring gene protein HokE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of the PhoPQ regulon in Escherichia coli and Salmonella typhimurium. Monsieurs P, et al. J Mol Evol, 2005 Apr. PMID 15883881
    2. YbdK is a carboxylate-amine ligase with a gamma-glutamyl:Cysteine ligase activity: crystal structure and enzymatic assays. Lehmann C, et al. Proteins, 2004 Aug 1. PMID 15211520
    3. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
    4. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutamate-cysteine ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glutamate-cysteine ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity, forming carbon-nitrogen bonds IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ligase activity, forming carbon-nitrogen bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in modified amino acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative glutamate--cysteine ligase 2
    NP_415113.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      606265..607383 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415113.1 putative glutamate--cysteine ligase 2 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415113.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377FCC3
      Conserved Domains (1) summary
      PRK13516
      Location:1 → 372
      PRK13516; gamma-glutamyl:cysteine ligase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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