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    fbaB fructose-bisphosphate aldolase class I [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946632, updated on 3-Dec-2024

    Summary

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    Official Symbol
    fbaB
    Official Full Name
    fructose-bisphosphate aldolase class I
    Primary source
    ECOCYC:G7129
    Locus tag
    b2097
    See related
    ASAP:ABE-0006941
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    dhnA; ECK2090
    Summary
    The typical class I aldolases of plants and animals have been throroughly studied Fructose-1,6-bisphosphate aldolases can be divided into two classes on the basis of their catalytic and structural properties. [More information is available at EcoCyc: G7129].
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    Genomic context

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    Sequence:
    NC_000913.3 (2177512..2178564, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative tagatose-1,6-bisphosphate aldolase 2 chaperone Neighboring gene tagatose-1,6-bisphosphate aldolase 2 Neighboring gene putative transporter YegT Neighboring gene putative ADP-ribosylglycohydrolase YegU Neighboring gene putative sugar kinase YegV Neighboring gene putative DNA-binding transcriptional regulator YegW

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase. Thomson GJ, et al. Biochem J, 1998 Apr 15. PMID 9531482, Free PMC Article
    2. Novel kinetic and structural properties of the class-I D-fructose 1,6-bisphosphate aldolase from Escherichia coli (Crookes' strain). Baldwin SA, et al. Biochem J, 1978 Mar 1. PMID 348198, Free PMC Article
    3. Phosphate modification of fructose-1,6-bisphosphate aldolase in Escherichia coli. Babul J, et al. Biochem Biophys Res Commun, 1988 Mar 30. PMID 3281666
    4. Glucose metabolism in Escherichia coli and the effect of increased amount of aldolase. Babul J, et al. Biochemistry, 1993 May 4. PMID 8485146
    5. Comparison of the mechanisms of two distinct aldolases from Escherichia coli grown on gluconeogenic substrates. Scamuffa MD, et al. Biochim Biophys Acta, 1980 Aug 7. PMID 6996735

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fructose-bisphosphate aldolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables fructose-bisphosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane HDA PubMed 

    General protein information

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    Preferred Names
    fructose-bisphosphate aldolase class I
    NP_416600.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2177512..2178564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416600.4 fructose-bisphosphate aldolase class I [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416600.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376M5Z9, A0A377DRU1, A0A5N3D5X6
      Conserved Domains (1) summary
      PRK09250
      Location:1 → 350
      PRK09250; class I fructose-bisphosphate aldolase
    Nucleotide Protein
    Heading Accession and Version

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