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    yojI ABC transporter family protein/microcin J25 efflux protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946705, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yojI
    Official Full Name
    ABC transporter family protein/microcin J25 efflux protein
    Primary source
    ECOCYC:EG12070
    Locus tag
    b2211
    See related
    ASAP:ABE-0007303
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2203; yojJ
    Summary
    Overexpressed YojI confers Microcin J25 resistance and a yojI mutation confers Microcin J25 sensistivity. [More information is available at EcoGene: EG12070]. YojI is a member of the ABC superfamily of transporters . [More information is available at EcoCyc: EG12070].
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    Genomic context

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    Sequence:
    NC_000913.3 (2306972..2308615, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene serine protease inhibitor ecotin Neighboring gene malate:quinone oxidoreductase Neighboring gene DNA oxidative demethylase Neighboring gene DNA-binding transcriptional dual regulator/DNA repair protein Ada

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protective action of ppGpp in microcin J25-sensitive strains. Pomares MF, et al. J Bacteriol, 2008 Jun. PMID 18408024, Free PMC Article
    2. Microbial genome analyses: global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities. Paulsen IT, et al. J Mol Biol, 1998 Apr 3. PMID 9533881
    3. YojI of Escherichia coli functions as a microcin J25 efflux pump. Delgado MA, et al. J Bacteriol, 2005 May. PMID 15866933, Free PMC Article
    4. Novel macrolide-specific ABC-type efflux transporter in Escherichia coli. Kobayashi N, et al. J Bacteriol, 2001 Oct. PMID 11544226, Free PMC Article
    5. Effect of drug transporter genes on cysteine export and overproduction in Escherichia coli. Yamada S, et al. Appl Environ Microbiol, 2006 Jul. PMID 16820466, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptide transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within microcin transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to antibiotic IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ABC transporter family protein/microcin J25 efflux protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2306972..2308615 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416715.1 ABC transporter family protein/microcin J25 efflux protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416715.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1V2GIT8, A0A5D8MW63
      Conserved Domains (1) summary
      PRK10522
      Location:1 → 547
      PRK10522; multidrug transporter membrane component/ATP-binding component; Provisional
    Nucleotide Protein
    Heading Accession and Version

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