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    hcaB 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945346, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hcaB
    Official Full Name
    2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
    Primary source
    ECOCYC:G7335
    Locus tag
    b2541
    See related
    ASAP:ABE-0008361
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2538; phdD; yfhX
    Summary
    Hydrocinnamic acid is a synonym for 3-phenylpropionic acid. [More information is available at EcoGene: EG13459]. The subunit structure is unknown. [More information is available at EcoCyc: G7335].
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    Genomic context

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    Sequence:
    NC_000913.3 (2671225..2672037)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein IroK Neighboring gene DNA-binding transcriptional dual regulator HcaR Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase subunit alpha Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase subunit beta Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin subunit Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin reductase subunit Neighboring gene putative inner membrane protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 3-phenylpropionate catabolism and the Escherichia coli oxidative stress response. Turlin E, et al. Res Microbiol, 2005 Apr. PMID 15808934
    2. Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli. Burlingame R, et al. J Bacteriol, 1983 Jul. PMID 6345502, Free PMC Article
    3. Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation. Burlingame RP, et al. J Bacteriol, 1986 Oct. PMID 3531186, Free PMC Article
    4. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz E, et al. J Bacteriol, 1998 Jun. PMID 9603882, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 3-phenylpropionate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within 3-phenylpropionate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
    NP_417036.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2671225..2672037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417036.1 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417036.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P0CI32
      Conserved Domains (1) summary
      cd05348
      Location:3 → 259
      BphB-like_SDR_c; cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs
    Nucleotide Protein
    Heading Accession and Version

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