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    hycB formate hydrogenlyase subunit HycB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948002, updated on 3-Dec-2024

    Summary

    Official Symbol
    hycB
    Official Full Name
    formate hydrogenlyase subunit HycB
    Primary source
    ECOCYC:EG10475
    Locus tag
    b2724
    See related
    ASAP:ABE-0008950
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2719; hevB
    Summary
    FhlA regulon. [More information is available at EcoGene: EG10475]. HycB is thought to code for a subunit of hydrogenase 3, a peptide of the [4Fe-4S] ferredoxin type, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase . [More information is available at EcoCyc: EG10475].
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    Genomic context

    Sequence:
    NC_000913.3 (2849238..2849849, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene formate hydrogenlyase subunit HycE Neighboring gene formate hydrogenlyase subunit HycD Neighboring gene formate hydrogenlyase subunit HycC Neighboring gene regulator of the transcriptional regulator FhlA Neighboring gene hydrogenase 3 nickel incorporation protein HypA

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables 4 iron, 4 sulfur cluster binding RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in anaerobic electron transport chain IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in anaerobic respiration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in formate oxidation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in glucose catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of formate dehydrogenase complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    formate hydrogenlyase subunit HycB
    NP_417204.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2849238..2849849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417204.1 formate hydrogenlyase subunit HycB [Escherichia coli str. K-12 substr. MG1655]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376D3R9, A0A376MGR1
      Conserved Domains (1) summary
      cd10554
      Location:4167
      HycB_like; HycB, HydN and similar proteins