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    nirC nitrite transporter NirC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847757, updated on 17-Dec-2024

    Summary

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    Official Symbol
    nirC
    Official Full Name
    nitrite transporter NirC
    Primary source
    ECOCYC:EG10654
    Locus tag
    b3367
    See related
    ASAP:ABE-0011008
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3355
    Summary
    NirC is a nitrite transporter which is a member of the FNT family of formate and nitrite transporters . [More information is available at EcoCyc: EG10654].
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    Genomic context

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    Sequence:
    NC_000913.3 (3497003..3497809)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter TsgA Neighboring gene nitrite reductase (NADH) large subunit Neighboring gene nitrite reductase (NADH) small subunit Neighboring gene siroheme synthase Neighboring gene DUF4223 domain-containing lipoprotein YhfL

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanism of nitrite transporter NirC in motility, biofilm formation, and adhesion of avian pathogenic Escherichia coli. Liu J, et al. Arch Microbiol, 2021 Sep. PMID 34091701
    2. Suppression of FNR-dependent transcription activation at the Escherichia coli nir promoter by Fis, IHF and H-NS: modulation of transcription initiation by a complex nucleo-protein assembly. Browning DF, et al. Mol Microbiol, 2000 Sep. PMID 10972841
    3. Transcriptional control of the cysG gene of Escherichia coli K-12 during aerobic and anaerobic growth. Peakman T, et al. Eur J Biochem, 1990 Jul 31. PMID 2200673
    4. Cloning of binding sequences for the Escherichia coli transcription activators, FNR and CRP: location of bases involved in discrimination between FNR and CRP. Bell AI, et al. Nucleic Acids Res, 1989 May 25. PMID 2543955, Free PMC Article
    5. Role of the Escherichia coli nitrate transport protein, NarU, in survival during severe nutrient starvation and slow growth. Clegg SJ, et al. Microbiology (Reading), 2006 Jul. PMID 16804183

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mechanism of nitrite transporter NirC in motility, biofilm formation, and adhesion of avian pathogenic Escherichia coli.
      Title: Mechanism of nitrite transporter NirC in motility, biofilm formation, and adhesion of avian pathogenic Escherichia coli.
    2. A NarU+ NirC+ strain grew more rapidly and accumulated nitrite more rapidly than the isogenic NarU+ NirC(-) strain. Only the NirC+ strain consumed nitrite rapidly during the later stages of growth.
      Title: A single channel for nitrate uptake, nitrite export and nitrite uptake by Escherichia coli NarU and a role for NirC in nitrite export and uptake.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables formate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nitrite transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in formate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nitrate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nitrite transport EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nitrite transporter NirC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3497003..3497809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026212.2 nitrite transporter NirC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026212.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAN3MB84
      Conserved Domains (1) summary
      PRK11562
      Location:1 → 268
      PRK11562; nitrite transporter NirC; Provisional
    Nucleotide Protein
    Heading Accession and Version

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