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    cysG siroheme synthase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947880, updated on 3-Dec-2024

    Summary

    Official Symbol
    cysG
    Official Full Name
    siroheme synthase
    Primary source
    ECOCYC:EG10188
    Locus tag
    b3368
    See related
    ASAP:ABE-0011010
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3356
    Summary
    YraL is homologous to the C-terminal methyltransferase domain of CysG. cysG is transcribed from the nirB operon and from cysG promoters. [More information is available at EcoGene: EG10188]. The Escherichia coli |FRAME: [More information is available at EcoCyc: EG10188].
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    Genomic context

    Sequence:
    NC_000913.3 (3497828..3499201)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene nitrite reductase (NADH) large subunit Neighboring gene nitrite reductase (NADH) small subunit Neighboring gene nitrite transporter NirC Neighboring gene DUF4223 domain-containing lipoprotein YhfL Neighboring gene fructoselysine/psicoselysine transporter

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ferrochelatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables precorrin-2 dehydrogenase activity EXP
    Inferred from Experiment
    more info
    PubMed 
    enables precorrin-2 dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sirohydrochlorin ferrochelatase activity EXP
    Inferred from Experiment
    more info
    PubMed 
    enables sirohydrochlorin ferrochelatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables uroporphyrin-III C-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables uroporphyrin-III C-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables uroporphyrin-III C-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cobalamin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in porphyrin-containing compound biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within siroheme biosynthetic process EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in siroheme biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in siroheme biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3497828..3499201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417827.1 siroheme synthase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417827.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3P5DV28, A0A8S7EAT8
      Conserved Domains (1) summary
      PRK10637
      Location:1457
      cysG; siroheme synthase CysG