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    rbbA ribosome-associated ATPase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947998, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rbbA
    Official Full Name
    ribosome-associated ATPase
    Primary source
    ECOCYC:EG12223
    Locus tag
    b3486
    See related
    ASAP:ABE-0011381
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3471; yhiG; yhiH
    Summary
    RbbA is homologous to the ABC-type transporter family, but has no overexpression resistance phenotype and is not a membrane transporter. [More information is available at EcoGene: EG12223]. RbbA is associated with the 30S subunit of the ribosome and has ribosome-dependent ATPase activity . [More information is available at EcoCyc: EG12223].
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    Genomic context

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    Sequence:
    NC_000913.3 (3626803..3629538, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transposase Neighboring gene ABC transporter family protein YhhJ Neighboring gene putative membrane fusion protein YhiI Neighboring gene protein YhiY Neighboring gene DUF4049 domain-containing protein YhiJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular localization of a ribosome-dependent ATPase on Escherichia coli ribosomes. Xu J, et al. Nucleic Acids Res, 2006. PMID 16495476, Free PMC Article
    2. Isolation and point of action of a factor from Escherichia coli required to reconstruct translation. Ganoza MC, et al. Proc Natl Acad Sci U S A, 1985 Mar. PMID 3885216, Free PMC Article
    3. Requirements for in vitro reconstruction of protein synthesis. Green RH, et al. Biochem Biophys Res Commun, 1985 Jan 31. PMID 3884000
    4. A new factor from Escherichia coli affects translocation of mRNA. Ganoza MC, et al. J Biol Chem, 1995 Nov 3. PMID 7592851
    5. A ribosomal ATPase is a target for hygromycin B inhibition on Escherichia coli ribosomes. Ganoza MC, et al. Antimicrob Agents Chemother, 2001 Oct. PMID 11557474, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A truncated form of the RbbA protein binds at the E-site of ribosomes.
      Title: Molecular localization of a ribosome-dependent ATPase on Escherichia coli ribosomes.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ribosomal small subunit binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell pole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosome-associated ATPase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3626803..3629538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026225.1 ribosome-associated ATPase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026225.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FVK4
      Conserved Domains (1) summary
      NF033858
      Location:12 → 910
      ABC2_perm_RbbA; ribosome-associated ATPase/putative transporter RbbA
    Nucleotide Protein
    Heading Accession and Version

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