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    ulaF L-ribulose-5-phosphate 4-epimerase UlaF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948711, updated on 17-Dec-2024

    Summary

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    Official Symbol
    ulaF
    Official Full Name
    L-ribulose-5-phosphate 4-epimerase UlaF
    Primary source
    ECOCYC:G7860
    Locus tag
    b4198
    See related
    ASAP:ABE-0013734
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4194; sgaE; yjfX
    Summary
    The ula divergon is comprised of the two divergent ulaGR and ulaABCDEF operons. [More information is available at EcoGene: EG12498]. L-ribulose 5-phosphate 4-epimerase is an enzyme in the pathway of anaerobic L-ascorbate degradation . [More information is available at EcoCyc: G7860].
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    Genomic context

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    Sequence:
    NC_000913.3 (4423700..4424386)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-ascorbate specific PTS enzyme IIA component Neighboring gene 3-keto-L-gulonate-6-phosphate decarboxylase UlaD Neighboring gene L-ribulose-5-phosphate 3-epimerase UlaE Neighboring gene DUF1471 domain-containing protein YjfY Neighboring gene 30S ribosomal subunit protein S6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aerobic L-ascorbate metabolism and associated oxidative stress in Escherichia coli. Campos E, et al. Microbiology (Reading), 2007 Oct. PMID 17906139
    2. The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli. Campos E, et al. J Bacteriol, 2002 Nov. PMID 12374842, Free PMC Article
    3. The ascorbate transporter of Escherichia coli. Zhang Z, et al. J Bacteriol, 2003 Apr. PMID 12644495, Free PMC Article
    4. Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli. Campos E, et al. J Bacteriol, 2004 Mar. PMID 14996803, Free PMC Article
    5. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-ribulose-phosphate 4-epimerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-ribulose-phosphate 4-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aldehyde-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-ascorbic acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within L-ascorbic acid metabolic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in monosaccharide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pentose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    L-ribulose-5-phosphate 4-epimerase UlaF
    NP_418619.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4423700..4424386
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418619.1 L-ribulose-5-phosphate 4-epimerase UlaF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418619.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1MX52, A0A7A6KFJ7, A0A8S7EAR9
      Conserved Domains (1) summary
      PRK12348
      Location:1 → 228
      sgaE; L-ribulose-5-phosphate 4-epimerase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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