U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dmlR DNA-binding transcriptional regulator DmlR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946316, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    dmlR
    Official Full Name
    DNA-binding transcriptional regulator DmlR
    Primary source
    ECOCYC:G6985
    Locus tag
    b1799
    See related
    ASAP:ABE-0005987
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1797; yeaT
    Summary
    LysR family. [More information is available at EcoGene: EG13506]. YeaT is a predicted regulator that is required for growth on D-malate as the sole carbon source under high-throughput growth conditions with limited aeration. [More information is available at EcoCyc: G6985].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1880886..1881809, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF1971 domain-containing protein YeaR Neighboring gene leucine exporter Neighboring gene D-malate/3-isopropylmalate dehydrogenase (decarboxylating) Neighboring gene putative transporter YeaV

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The yeaS (leuE) gene of Escherichia coli encodes an exporter of leucine, and the Lrp protein regulates its expression. Kutukova EA, et al. FEBS Lett, 2005 Aug 29. PMID 16098526
    2. Beta-barrel proteins that reside in the Escherichia coli outer membrane in vivo demonstrate varied folding behavior in vitro. Burgess NK, et al. J Biol Chem, 2008 Sep 26. PMID 18641391, Free PMC Article
    3. Regulation of aerobic and anaerobic D-malate metabolism of Escherichia coli by the LysR-type regulator DmlR (YeaT). Lukas H, et al. J Bacteriol, 2010 May. PMID 20233924, Free PMC Article
    4. Systems approach to refining genome annotation. Reed JL, et al. Proc Natl Acad Sci U S A, 2006 Nov 14. PMID 17088549, Free PMC Article
    5. Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea. Pérez-Rueda E, et al. Comput Biol Chem, 2004 Dec. PMID 15556475

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within malate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in malate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-binding transcriptional regulator DmlR

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1880886..1881809 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416313.4 DNA-binding transcriptional regulator DmlR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416313.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9QAD4
      Conserved Domains (2) summary
      cd08479
      Location:95 → 291
      PBP2_CrgA_like_9; The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold
      pfam00126
      Location:7 → 66
      HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.