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    ghoS antitoxin of the GhoTS toxin-antitoxin system [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948646, updated on 17-Dec-2024

    Summary

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    Official Symbol
    ghoS
    Official Full Name
    antitoxin of the GhoTS toxin-antitoxin system
    Primary source
    ECOCYC:G7830
    Locus tag
    b4128
    See related
    ASAP:ABE-0013518
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4121; yjdK
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    Genomic context

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    Sequence:
    NC_000913.3 (4352584..4352880)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF06902 family protein YjdI Neighboring gene putative N-acetyltransferase YjdJ Neighboring gene toxin of the GhoTS toxin-antitoxin system Neighboring gene lysine--tRNA ligase/Ap4A synthetase/Ap3A synthetase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell membrane to reduce adenosine triphosphate and to reduce growth under stress. Cheng HY, et al. Environ Microbiol, 2014 Jun. PMID 24373067
    2. A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS. Wang X, et al. Nat Chem Biol, 2012 Oct. PMID 22941047, Free PMC Article
    3. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article
    4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
    5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The GhoT/GhoS toxin/antitoxin system protects the cell from antimicrobials.
      Title: Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell membrane to reduce adenosine triphosphate and to reduce growth under stress.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables RNA endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    antitoxin of the GhoTS toxin-antitoxin system

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4352584..4352880
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418552.1 antitoxin of the GhoTS toxin-antitoxin system [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418552.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5N3D729
      Conserved Domains (1) summary
      pfam11080
      Location:8 → 94
      GhoS; Endoribonuclease GhoS
    Nucleotide Protein
    Heading Accession and Version

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