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    ynfL putative DNA-binding transcriptional regulator YnfL [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946136, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ynfL
    Official Full Name
    putative DNA-binding transcriptional regulator YnfL
    Primary source
    ECOCYC:G6853
    Locus tag
    b1595
    See related
    ASAP:ABE-0005326
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1590
    Summary
    A ynfLM clone conferred hypersensitivity to acriflavin, but a ynfM-alone expression clone did not, leading the authors to conclude that overexpression of the putative regulator YnfL was responsible for the Acr-S phenoptype. [More information is available at EcoGene: EG13850].
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    Genomic context

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    Sequence:
    NC_000913.3 (1668699..1669592, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative chloride:H(+) antiporter ClcB Neighboring gene dethiobiotin synthetase BidA Neighboring gene DNA-binding transcriptional repressor Mlc Neighboring gene putative transporter YnfM Neighboring gene periplasmic chaperone Asr

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of a complete library of putative drug transporter genes in Escherichia coli. Nishino K, et al. J Bacteriol, 2001 Oct. PMID 11566977, Free PMC Article
    2. The repertoire of DNA-binding transcriptional regulators in Escherichia coli K-12. Pérez-Rueda E, et al. Nucleic Acids Res, 2000 Apr 15. PMID 10734204, Free PMC Article
    3. Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea. Pérez-Rueda E, et al. Comput Biol Chem, 2004 Dec. PMID 15556475
    4. Global analysis of candidate genes important for fitness in a competitive biofilm using DNA-array-based transposon mapping. Junker LM, et al. Microbiology (Reading), 2006 Aug. PMID 16849790
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-DNA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative DNA-binding transcriptional regulator YnfL

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1668699..1669592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416112.1 putative DNA-binding transcriptional regulator YnfL [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416112.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6M9WVL8
      Conserved Domains (2) summary
      cd08414
      Location:94 → 289
      PBP2_LTTR_aromatics_like; The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold
      pfam00126
      Location:5 → 64
      HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family
    Nucleotide Protein
    Heading Accession and Version

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