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    gntT high-affinity gluconate transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947924, updated on 3-Dec-2024

    Summary

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    Official Symbol
    gntT
    Official Full Name
    high-affinity gluconate transporter
    Primary source
    ECOCYC:EG12380
    Locus tag
    b3415
    See related
    ASAP:ABE-0011148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3402; gntM; gntTalpha; usgA; yhgC
    Summary
    IT (Ion Transporter) superfamily (Prakash, 2003). [More information is available at EcoGene: EG12380]. GntT is one of four known transporters for gluconate in Escherichia coli, the others being the homologous GntU, GntP and IdnT transporters. [More information is available at EcoCyc: EG12380].
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    Genomic context

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    Sequence:
    NC_000913.3 (3546559..3547875)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA utilization protein YhgH Neighboring gene iron-sulfur cluster carrier protein NfuA Neighboring gene 4-alpha-glucanotransferase Neighboring gene maltodextrin phosphorylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selection of lacZ operon fusions in genes of gluconate metabolism in E. coli. characterization of a gntT::lacZ fusion. Porco A, et al. Acta Cient Venez, 1991. PMID 1843569
    2. A mutation affecting gluconate catabolism in Escherichia coli: the locus for the main high affinity transport. De Rekarte UD, et al. Acta Cient Venez, 1994. PMID 8731292
    3. Positive and negative transcriptional regulation of the Escherichia coli gluconate regulon gene gntT by GntR and the cyclic AMP (cAMP)-cAMP receptor protein complex. Peekhaus N, et al. J Bacteriol, 1998 Apr. PMID 9537375, Free PMC Article
    4. Mutations affecting gluconate catabolism in Escherichia coli. Genetic mapping of the locus for the thermosensitive gluconokinase. Istúriz T, et al. J Gen Microbiol, 1986 Nov. PMID 3040894
    5. Mutations affecting gluconate metabolism in Escherichia coli. Nagel de Zwaig R, et al. J Bacteriol, 1973 May. PMID 4574689, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables gluconate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gluconate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables gluconate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-gluconate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in D-gluconate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gluconate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in gluconate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gluconate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    high-affinity gluconate transporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3546559..3547875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026217.1 high-affinity gluconate transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026217.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376VAQ2
      Conserved Domains (1) summary
      PRK14984
      Location:1 → 438
      PRK14984; gluconate transporter
    Nucleotide Protein
    Heading Accession and Version

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