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    yiaK 2,3-diketo-L-gulonate reductase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948096, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yiaK
    Official Full Name
    2,3-diketo-L-gulonate reductase
    Primary source
    ECOCYC:EG12279
    Locus tag
    b3575
    See related
    ASAP:ABE-0011682
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3564
    Summary
    The yiaK gene encodes a 2,3-diketo-L-gulonate reductase . [More information is available at EcoCyc: EG12279].
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    Genomic context

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    Sequence:
    NC_000913.3 (3742733..3743731)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative electron transport protein YsaA Neighboring gene DNA-binding transcriptional repressor PlaR Neighboring gene DUF386 domain-containing protein YiaL Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - membrane subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel NAD-binding protein revealed by the crystal structure of 2,3-diketo-L-gulonate reductase (YiaK). Forouhar F, et al. J Biol Chem, 2004 Mar 26. PMID 14718529
    2. A rare 920-kilobase chromosomal inversion mediated by IS1 transposition causes constitutive expression of the yiaK-S operon for carbohydrate utilization in Escherichia coli. Badía J, et al. J Biol Chem, 1998 Apr 3. PMID 9525947
    3. Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli. Tavazoie S, et al. Nat Biotechnol, 1998 Jun. PMID 9624689
    4. Regulation of expression of the yiaKLMNOPQRS operon for carbohydrate utilization in Escherichia coli: involvement of the main transcriptional factors. Ibañez E, et al. J Bacteriol, 2000 Aug. PMID 10913096, Free PMC Article
    5. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    2,3-diketo-L-gulonate reductase
    NP_418032.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3742733..3743731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418032.1 2,3-diketo-L-gulonate reductase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418032.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FUJ5
      Conserved Domains (1) summary
      PRK13260
      Location:1 → 332
      PRK13260; 2,3-diketo-L-gulonate reductase; Provisional
    Nucleotide Protein
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