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    dcuC anaerobic C4-dicarboxylate transporter DcuC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945000, updated on 17-Dec-2024

    Summary

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    Official Symbol
    dcuC
    Official Full Name
    anaerobic C4-dicarboxylate transporter DcuC
    Primary source
    ECOCYC:G6347
    Locus tag
    b0621
    See related
    ASAP:ABE-0002133
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0614
    Summary
    IT (Ion Transporter) superfamily (Prakash, 2003). [More information is available at EcoGene: EG13545]. DcuC is the prototype of the DcuC family of dicarboxylate uptake transporters. [More information is available at EcoCyc: G6347].
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    Genomic context

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    Sequence:
    NC_000913.3 (654583..655968, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene citrate lyase synthetase Neighboring gene sensor histidine kinase DpiB Neighboring gene DNA-binding transcriptional dual regulator DpiA Neighboring gene Lipid A palmitoyltransferase Neighboring gene transcription antiterminator and regulator of RNA stability CspE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The dcuD (former yhcL) gene product of escherichia coli as a member of the DcuC family of C4-dicarboxylate carriers: lack of evident expression. Janausch IG, et al. Arch Microbiol, 1999 Oct. PMID 10525738
    2. Anaerobic fumarate transport in Escherichia coli by an fnr-dependent dicarboxylate uptake system which is different from the aerobic dicarboxylate uptake system. Engel P, et al. J Bacteriol, 1992 Sep. PMID 1512189, Free PMC Article
    3. Transport of C4-dicarboxylates by anaerobically grown Escherichia coli. Energetics and mechanism of exchange, uptake and efflux. Engel P, et al. Eur J Biochem, 1994 Jun 1. PMID 8020497
    4. DctA- and Dcu-independent transport of succinate in Escherichia coli: contribution of diffusion and of alternative carriers. Janausch IG, et al. Arch Microbiol, 2001 Sep. PMID 11511871
    5. The ion transporter superfamily. Prakash S, et al. Biochim Biophys Acta, 2003 Dec 3. PMID 14643936

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables C4-dicarboxylate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables succinate:fumarate antiporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in C4-dicarboxylate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in C4-dicarboxylate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within C4-dicarboxylate transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in fumarate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mixed acid fermentation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in succinate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    anaerobic C4-dicarboxylate transporter DcuC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      654583..655968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415154.1 anaerobic C4-dicarboxylate transporter DcuC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415154.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1NQI0
      Conserved Domains (1) summary
      PRK10654
      Location:1 → 455
      dcuC; C4-dicarboxylate transporter DcuC; Provisional
    Nucleotide Protein
    Heading Accession and Version

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