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    uidB glucuronide:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947484, updated on 3-Dec-2024

    Summary

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    Official Symbol
    uidB
    Official Full Name
    glucuronide:H(+) symporter
    Primary source
    ECOCYC:EG11658
    Locus tag
    b1616
    See related
    ASAP:ABE-0005407
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1611; gusB; uidP
    Summary
    Transport activity is enhanced by putative porin UidC. [More information is available at EcoGene: EG11658]. UidB, also known as GusB, is a proton-dependent transporter specific for - and -glucuronides . [More information is available at EcoCyc: EG11658].
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    Genomic context

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    Sequence:
    NC_000913.3 (1692890..1694263, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF945 domain-containing protein YdgA Neighboring gene outer membrane porin family protein UidC Neighboring gene beta-glucuronidase Neighboring gene DNA-binding transcriptional repressor UidR Neighboring gene 7-alpha-hydroxysteroid dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Investigation on stability of transporter protein, glucuronide transporter from Escherichia coli. Ishii N. J Membr Biol, 2010 Jun. PMID 20490474
    2. The gusBC genes of Escherichia coli encode a glucuronide transport system. Liang WJ, et al. J Bacteriol, 2005 Apr. PMID 15774881, Free PMC Article
    3. beta-Glucuronidase from Escherichia coli as a gene-fusion marker. Jefferson RA, et al. Proc Natl Acad Sci U S A, 1986 Nov. PMID 3534890, Free PMC Article
    4. Active membrane transport and receptor proteins from bacteria. Saidijam M, et al. Biochem Soc Trans, 2005 Aug. PMID 16042616
    5. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. It is likely that GusB resides in the membrane as a pentamer.
      Title: Investigation on stability of transporter protein, glucuronide transporter from Escherichia coli.
    2. Isolation, function, and mapping of the gene in a naturally-occuring E. coli strain.
      Title: The gusBC genes of Escherichia coli encode a glucuronide transport system.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucuronide:H(+) symporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1692890..1694263 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416133.1 glucuronide:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416133.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7A2XWR7
      Conserved Domains (1) summary
      PRK09848
      Location:1 → 448
      PRK09848; glucuronide transporter; Provisional
    Nucleotide Protein
    Heading Accession and Version

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