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    argA N-acetylglutamate synthase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947289, updated on 17-Dec-2024

    Summary

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    Official Symbol
    argA
    Official Full Name
    N-acetylglutamate synthase
    Primary source
    ECOCYC:EG10063
    Locus tag
    b2818
    See related
    ASAP:ABE-0009245
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    Arg1; Arg2; ECK2814
    Summary
    N-acetylglutamate synthase (ArgA) carries out the first steps in the superpathway of arginine biosynthesis and the pathway of ornithine biosynthesis. [More information is available at EcoCyc: EG10063].
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    Genomic context

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    Sequence:
    NC_000913.3 (2949242..2950573)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Met Neighboring gene N-acetylmuramoyl-L-alanine amidase C Neighboring gene exodeoxyribonuclease V subunit RecD Neighboring gene exodeoxyribonuclease V subunit RecB Neighboring gene protease 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. N-acetylglutamate synthase of Escherichia coli: purification, characterization, and molecular properties. Marvil DK, et al. J Biol Chem, 1977 May 25. PMID 16890
    2. Expression of the argA gene carried by a defective lambda bacteriophage of Escherichia coli. Leisinger T, et al. J Bacteriol, 1976 Mar. PMID 130376, Free PMC Article
    3. N-Acetylglutamate synthase of Escherichia coli regulation of synthesis and activity by arginine. Leisinger T, et al. J Biol Chem, 1975 Mar 10. PMID 1089665
    4. Isolation and characterization of mutants with a feedback resistant N-acetylglutamate synthase in Escherichia coli K 12. Eckhardt T, et al. Mol Gen Genet, 1975 Jun 19. PMID 1102931
    5. Identification of oligomerizing peptides. Dhiman A, et al. J Biol Chem, 2001 Jun 8. PMID 11274194

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Complete nucleotide sequence of the Escherichia coli argA gene.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-glutamate N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutamate N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-arginine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in L-arginine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within L-arginine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    N-acetylglutamate synthase
    NP_417295.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2949242..2950573
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417295.1 N-acetylglutamate synthase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417295.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2W6PET9
      Conserved Domains (1) summary
      PRK05279
      Location:1 → 442
      PRK05279; N-acetylglutamate synthase; Validated
    Nucleotide Protein
    Heading Accession and Version

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