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    rpsM 30S ribosomal subunit protein S13 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947791, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rpsM
    Official Full Name
    30S ribosomal subunit protein S13
    Primary source
    ECOCYC:EG10912
    Locus tag
    b3298
    See related
    ASAP:ABE-0010809
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3285
    Summary
    rpsM can be deleted, but null mutants grow slowly and express kanamycin resistance weakly (Bubunenko, 2007), which may explain why a deletion was not isolated by Baba (2006), leading to its misclassification as an essential gene. [More information is available at EcoGene: EG10912]. The S13 protein is a component of the 30S subunit of the ribosome, playing a key role in subunit association and the fidelity of translocation. [More information is available at EcoCyc: EG10912].
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    Genomic context

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    Sequence:
    NC_000913.3 (3442115..3442471, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 30S ribosomal subunit protein S4 Neighboring gene 30S ribosomal subunit protein S11 Neighboring gene 50S ribosomal subunit protein L36 Neighboring gene Sec translocon subunit SecY

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Primary structure of protein S13 from the small subunit of escherichia coli ribosomes. Lindemann H, et al. Hoppe Seylers Z Physiol Chem, 1977 Jul. PMID 330375
    2. Growth-rate-dependent regulation of ribosome synthesis in E. coli: expression of the lacZ and galK genes fused to ribosomal promoters. Miura A, et al. Cell, 1981 Sep. PMID 6793240
    3. Antisuppression by a mutation in rpsM(S13) giving a shortened ribosomal protein S13. Faxén M, et al. Biochim Biophys Acta, 1994 May 17. PMID 8193163
    4. Directed hydroxyl radical probing of the rRNA neighborhood of ribosomal protein S13 using tethered Fe(II). Heilek GM, et al. RNA, 1996 Jun. PMID 8718688, Free PMC Article
    5. The RNA binding properties of "native" protein-protein complexes isolated from the Escherichia coli ribosome. Dijk J, et al. FEBS Lett, 1977 May 15. PMID 324809

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Primary structure of protein S13 from the small subunit of escherichia coli ribosomes.
    2. results link S13 to the 3' major domain family of proteins, and the S7 assembly branch, placing S13 in a new location in the 30S subunit assembly map
      Title: Assembly of the 30S ribosomal subunit: positioning ribosomal protein S13 in the S7 assembly branch.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    30S ribosomal subunit protein S13

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3442115..3442471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417757.1 30S ribosomal subunit protein S13 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417757.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6L7C9R2
      Conserved Domains (1) summary
      PRK05179
      Location:1 → 118
      rpsM; 30S ribosomal protein S13; Validated
    Nucleotide Protein
    Heading Accession and Version

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