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    uhpB sensory histidine kinase UhpB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948195, updated on 17-Dec-2024

    Summary

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    Official Symbol
    uhpB
    Official Full Name
    sensory histidine kinase UhpB
    Primary source
    ECOCYC:EG11052
    Locus tag
    b3668
    See related
    ASAP:ABE-0011993
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3659
    Summary
    Probable false positive lipoprotein prediction, Cys not conserved, 10 CM TMs predicted. [More information is available at EcoGene: EG11052]. UhpB belongs to the phosphorelay system UhpB-UhpC-UhpA and is involved in the regulation of the uptake of hexose phosphates . [More information is available at EcoCyc: EG11052].
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    Genomic context

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    Sequence:
    NC_000913.3 (3848634..3850136, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene hexose-6-phosphate:phosphate antiporter Neighboring gene inner membrane protein sensing glucose-6-phosphate Neighboring gene DNA-binding transcriptional activator UhpA Neighboring gene acetohydroxy acid synthase I subunit IlvN Neighboring gene acetohydroxy acid synthase I subunit IlvB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The phosphoryl transfer domain of UhpB interacts with the response regulator UhpA. Wright JS 3rd, et al. J Bacteriol, 2001 May. PMID 11325944, Free PMC Article
    2. Promoter elements required for positive control of transcription of the Escherichia coli uhpT gene. Merkel TJ, et al. J Bacteriol, 1992 May. PMID 1569008, Free PMC Article
    3. Role of uhp genes in expression of the Escherichia coli sugar-phosphate transport system. Weston LA, et al. J Bacteriol, 1988 Aug. PMID 3042748, Free PMC Article
    4. Action of receiver and activator modules of UhpA in transcriptional control of the Escherichia coli sugar phosphate transport system. Webber CA, et al. Mol Microbiol, 1995 Mar. PMID 7596290
    5. The family of organo-phosphate transport proteins includes a transmembrane regulatory protein. Kadner RJ, et al. J Bioenerg Biomembr, 1993 Dec. PMID 8144492

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoprotein phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphorelay sensor kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphorelay sensor kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphorelay sensor kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphorelay signal transduction system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within signal transduction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sensory histidine kinase UhpB
    NP_418124.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3848634..3850136 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418124.4 sensory histidine kinase UhpB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418124.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3JAQ9, A0A376FUW3
      Conserved Domains (1) summary
      PRK11644
      Location:4 → 498
      PRK11644; signal transduction histidine-protein kinase/phosphatase UhpB
    Nucleotide Protein
    Heading Accession and Version

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