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    fdnG formate dehydrogenase N subunit alpha [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946035, updated on 3-Dec-2024

    Summary

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    Official Symbol
    fdnG
    Official Full Name
    formate dehydrogenase N subunit alpha
    Primary source
    ECOCYC:EG11227
    Locus tag
    b1474
    See related
    ASAP:ABE-0004917
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1468
    Summary
    FdnG is the catalytic subunit of formate dehydrogenase-N. [More information is available at EcoCyc: EG11227].
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    Genomic context

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    Sequence:
    NC_000913.3 (1547401..1550448)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative uncharacterized protein YddL Neighboring gene amino acid exporter YddG Neighboring gene formate dehydrogenase N subunit beta Neighboring gene formate dehydrogenase N subunit gamma Neighboring gene DNA-binding transcriptional regulator YddM

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. mRNA secondary structure modulates translation of Tat-dependent formate dehydrogenase N. Punginelli C, et al. J Bacteriol, 2004 Sep. PMID 15342602, Free PMC Article
    2. Anaerobic transport in Escherichia coli membrane vesicles. Boonstra J, et al. J Biol Chem, 1975 Sep 10. PMID 1099094
    3. Localization of upstream sequence elements required for nitrate and anaerobic induction of fdn (formate dehydrogenase-N) operon expression in Escherichia coli K-12. Li J, et al. J Bacteriol, 1992 Aug. PMID 1629153, Free PMC Article
    4. Purification and crystallization of the respiratory complex formate dehydrogenase-N from Escherichia coli. Jormakka M, et al. Acta Crystallogr D Biol Crystallogr, 2002 Jan. PMID 11752799
    5. SECISDesign: a server to design SECIS-elements within the coding sequence. Busch A, et al. Bioinformatics, 2005 Aug 1. PMID 15919727

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables electron transfer activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables formate dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables formate dehydrogenase (cytochrome-c-553) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables formate dehydrogenase (quinone) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables formate dehydrogenase (quinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molybdenum ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molybdenum ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables molybdopterin cofactor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables selenium binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anaerobic electron transport chain NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in anaerobic respiration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within anaerobic respiration IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular respiration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within formate oxidation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in formate oxidation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in heme oxidation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of formate dehydrogenase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of formate dehydrogenase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in membrane HDA PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    formate dehydrogenase N subunit alpha
    NP_415991.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1547401..1550448
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415991.1 formate dehydrogenase N subunit alpha [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415991.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7TUH5
      Conserved Domains (1) summary
      cl09928
      Location:2 → 1014
      Molybdopterin-Binding; Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and ...
    Nucleotide Protein
    Heading Accession and Version

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