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    chbF monoacetylchitobiose-6-phosphate hydrolase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946266, updated on 17-Dec-2024

    Summary

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    Official Symbol
    chbF
    Official Full Name
    monoacetylchitobiose-6-phosphate hydrolase
    Primary source
    ECOCYC:EG10144
    Locus tag
    b1734
    See related
    ASAP:ABE-0005785
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    celF; ECK1732; ydjD
    Summary
    The chb operon is induced by N,N'-diacetylchitobiose. [More information is available at EcoGene: EG10144]. ChbF is a diacetylchitobiose-6-phosphate hydrolase responsible for converting diacetylchitobiose-6-phosphate to N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate . [More information is available at EcoCyc: EG10144].
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    Genomic context

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    Sequence:
    NC_000913.3 (1817148..1818500, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene catalase HPII Neighboring gene chitooligosaccharide monodeacetylase ChbG Neighboring gene ChbR Neighboring gene N,N'-diacetylchitobiose-specific PTS enzyme IIA component

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chitin, Chitin Oligosaccharide, and Chitin Disaccharide Metabolism of Escherichia coli Revisited: Reassignment of the Roles of ChiA, ChbR, ChbF, and ChbG. Walter A, et al. Microb Physiol, 2021. PMID 33794535
    2. A luxAB transcriptional fusion to the cryptic celF gene of Escherichia coli displays increased luminescence in the presence of nickel. Guzzo A, et al. Mol Gen Genet, 1994 Feb. PMID 8121401
    3. Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose. Kachroo AH, et al. Mol Microbiol, 2007 Dec. PMID 18028317
    4. Directed evolution of cellobiose utilization in Escherichia coli K12. Kricker M, et al. Mol Biol Evol, 1984 Feb. PMID 6400650
    5. Biochemical genetics of the cryptic gene system for cellobiose utilization in Escherichia coli K12. Kricker M, et al. Genetics, 1987 Mar. PMID 3552873, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Cellobiose-6-phosphate hydrolase (CelF) of Escherichia coli: characterization and assignment to the unusual family 4 of glycosylhydrolases.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 6-phospho-beta-glucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 6-phospho-beta-glucosidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 6-phospho-beta-glucosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in diacetylchitobiose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    monoacetylchitobiose-6-phosphate hydrolase
    NP_416248.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1817148..1818500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416248.1 monoacetylchitobiose-6-phosphate hydrolase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416248.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376S8U2, A0A8S7SZ02
      Conserved Domains (1) summary
      cd05296
      Location:5 → 436
      GH4_P_beta_glucosidase; Glycoside Hydrolases Family 4; Phospho-beta-glucosidase
    Nucleotide Protein
    Heading Accession and Version

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