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    yfcE phosphodiesterase YfcE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946755, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yfcE
    Official Full Name
    phosphodiesterase YfcE
    Primary source
    ECOCYC:G7192
    Locus tag
    b2300
    See related
    ASAP:ABE-0007589
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2294
    Summary
    Phosphodiesterase activity of YfcE was discovered in a high-throughput screen of purified proteins. [More information is available at EcoCyc: G7192].
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    Genomic context

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    Sequence:
    NC_000913.3 (2419234..2419788, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YfcC Neighboring gene putative Nudix hydrolase YfcD Neighboring gene glutathione S-transferase YfcF Neighboring gene disulfide bond oxidoreductase YfcG

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A phosphate-binding histidine of binuclear metallophosphodiesterase enzymes is a determinant of 2',3'-cyclic nucleotide phosphodiesterase activity. Keppetipola N, et al. J Biol Chem, 2008 Nov 7. PMID 18757371, Free PMC Article
    2. Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene. Miller DJ, et al. Protein Sci, 2007 Jul. PMID 17586769, Free PMC Article
    3. Enzyme genomics: Application of general enzymatic screens to discover new enzymes. Kuznetsova E, et al. FEMS Microbiol Rev, 2005 Apr. PMID 15808744
    4. Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Lopez-Campistrous A, et al. Mol Cell Proteomics, 2005 Aug. PMID 15911532
    5. Protein abundance profiling of the Escherichia coli cytosol. Ishihama Y, et al. BMC Genomics, 2008 Feb 27. PMID 18304323, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables manganese ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoric diester hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphodiesterase YfcE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2419234..2419788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416803.3 phosphodiesterase YfcE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416803.3

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0H2Z1H6, A0A368ITH8, B7MG64, B7MXX8, Q1R9B3
      Conserved Domains (1) summary
      PRK09453
      Location:2 → 183
      PRK09453; phosphodiesterase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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